Abstract PD8-10: Efficacy and safety of enobosarm, a selective androgen receptor modulator, to target AR in women with advanced ER+/AR+ breast cancer - final results from an international Phase 2 randomized study

Abstract OT1-05-02: A phase II clinical trial of the combination of pembrolizumab and selective androgen receptor modulator GTx-024 in patients with advanced androgen receptor positive triple negative breast cancer

10.1158/1538-7445.sabcs17-ot1-05-02 ◽

2018 ◽

Cited By ~ 2

Author(s):

Y Yuan ◽

P Frankel ◽

T Synold ◽

P Lee ◽

S Yost ◽

...

Keyword(s):

Breast Cancer ◽

Clinical Trial ◽

Androgen Receptor ◽

Phase Ii ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Phase Ii Clinical Trial ◽

Abstract P4-13-02: Selective androgen receptor modulator RAD140 inhibits the growth of endocrine-resistant breast cancer models with defined genetic backgrounds

10.1158/1538-7445.sabcs18-p4-13-02 ◽

2019 ◽

Author(s):

Z Yu ◽

S He ◽

C Miller ◽

J Saeh ◽

G Hattersley ◽

...

Keyword(s):

Breast Cancer ◽

Androgen Receptor ◽

Receptor Modulator ◽

Cancer Models

Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor–Positive Breast Cancer Models with a Distinct Mechanism of Action

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-17-0670 ◽

2017 ◽

Vol 23 (24) ◽

pp. 7608-7620 ◽

Cited By ~ 10

Author(s):

Ziyang Yu ◽

Suqin He ◽

Dannie Wang ◽

Hitisha K. Patel ◽

Chris P. Miller ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Androgen Receptor ◽

Mechanism Of Action ◽

Receptor Modulator ◽

Distinct Mechanism ◽

Cancer Models ◽

Estrogen Receptor Positive ◽

Positive Breast Cancer

Abstract P5-05-01: Novel mechanisms of action of selective androgen receptor modulator RAD140 in AR+/ER+ breast cancer models

10.1158/1538-7445.sabcs19-p5-05-01 ◽

2020 ◽

Author(s):

Suqin He ◽

Maureen G Conlan ◽

Heike Arlt ◽

Charles Morris ◽

Ziyang Yu

Keyword(s):

Breast Cancer ◽

Androgen Receptor ◽

Mechanisms Of Action ◽

Receptor Modulator ◽

Cancer Models

RAD140, an orally available selective androgen receptor modulator, exhibits potent anti-tumor activity in ER+AR+ breast cancer models

European Journal of Cancer ◽

10.1016/s0959-8049(16)33042-8 ◽

2016 ◽

Vol 69 ◽

pp. S149

Author(s):

Z. Yu ◽

J. Brown ◽

J. Saeh ◽

G. Hattersley

Keyword(s):

Breast Cancer ◽

Androgen Receptor ◽

Receptor Modulator ◽

Cancer Models ◽

Anti Tumor Activity

A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia

The journal of nutrition health & aging ◽

10.1007/s12603-013-0335-x ◽

2013 ◽

Vol 17 (6) ◽

pp. 533-543 ◽

Cited By ~ 76

Author(s):

Dimitris A. Papanicolaou ◽

S. N. Ather ◽

H. Zhu ◽

Y. Zhou ◽

J. Lutkiewicz ◽

...

Keyword(s):

Clinical Trial ◽

Androgen Receptor ◽

Controlled Clinical Trial ◽

Efficacy And Safety ◽

Abstract OT2-01-07: A phase 2 open label, multi-center, multinational study investigating the efficacy and safety of GTx-024 on advanced, androgen receptor-positive triple negative breast cancer (AR+ TNBC)

10.1158/1538-7445.sabcs15-ot2-01-07 ◽

2016 ◽

Author(s):

H Rugo ◽

B Overmoyer ◽

L Schwartzberg ◽

C Palmieri ◽

R Taylor ◽

...

Keyword(s):

Breast Cancer ◽

Androgen Receptor ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Multinational Study ◽

Phase 2 ◽

Efficacy And Safety ◽

Open Label

A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+/HER2- Metastatic Breast Cancer

Clinical Breast Cancer ◽

10.1016/j.clbc.2021.08.003 ◽

2021 ◽

Author(s):

Patricia LoRusso ◽

Erika Hamilton ◽

Cynthia Ma ◽

Neelima Vidula ◽

Rebecca G. Bagley ◽

...

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Androgen Receptor ◽

Phase 1 ◽

Metastatic Breast ◽

Phase 1 Study ◽

Phase I dose escalation study of a selective androgen receptor modulator RAD140 in estrogen receptor positive (ER+), HER2 negative (HER2-) breast cancer (BC)

Annals of Oncology ◽

10.1093/annonc/mdz242.038 ◽

2019 ◽

Vol 30 ◽

pp. v123

Author(s):

E. Hamilton ◽

N. Vidula ◽

C. Ma ◽

P. LoRusso ◽

R.G. Bagley ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Androgen Receptor ◽

Phase I ◽

Dose Escalation ◽

Dose Escalation Study ◽

Receptor Modulator ◽

Her2 Breast Cancer ◽

Estrogen Receptor Positive

Abstract P6-12-06: Nonsteroidal, tissue selective androgen receptor modulator (SARM), enobosarm, reduces growth of androgen receptor-positive breast cancer in patient-derived preclinical models

10.1158/1538-7445.sabcs16-p6-12-06 ◽

2017 ◽

Author(s):

R Narayanan ◽

S Ponnusamy ◽

M Fan ◽

CH Yang ◽

BL Grimes ◽

...

Keyword(s):

Breast Cancer ◽

Androgen Receptor ◽

Preclinical Models ◽

Receptor Modulator ◽

Positive Breast Cancer