Antithrombin III and Platelets during the Normal Menstrual Cycle and in Women Receiving Oral Contraceptives Low in Oestrogen

1983 ◽  
Vol 15 (3) ◽  
pp. 153-162 ◽  
Author(s):  
Jørgen Jespersen ◽  
Steen Ingeberg ◽  
Elsa Bach
BMJ ◽  
1975 ◽  
Vol 4 (5995) ◽  
pp. 494-496 ◽  
Author(s):  
D Milligan ◽  
J O Drife ◽  
R V Short

2019 ◽  
Vol 17 (4) ◽  
pp. 763-770 ◽  
Author(s):  
Archana Boga ◽  
Fiona Stapleton ◽  
Nancy Briggs ◽  
Blanka Golebiowski

1981 ◽  
Vol 61 (4) ◽  
pp. 423-428 ◽  
Author(s):  
C. M. Perkins ◽  
K. W. Hancock ◽  
G. F. Cope ◽  
M. R. Lee

1. Urine free dopamine was estimated at predetermined points of the menstrual cycle in normal volunteer subjects and in women taking a combined oral contraceptive. 2. There was no alteration in 24 h urine dopamine during the normal menstrual cycle but, in contrast, combined oral contraceptives produced a fall which recovered premenstrually. 3. In 19 primigravid subjects 24 h urine free dopamine was estimated at monthly intervals throughout pregnancy and at the time of the postnatal examination. 4. Urine dopamine was elevated throughout pregnancy when compared with postnatal values. Women receiving an oral progestogen contraceptive at the time of the postnatal examination showed a further fall in urine dopamine.


1969 ◽  
Vol 43 (2) ◽  
pp. 217-224 ◽  
Author(s):  
RUTH M. STANDEVEN

SUMMARY Endogenous and exogenous oestrogenic effects on thyroid function tests were studied. [125I]Tri-iodothyronine charcoal uptake (T3 uptake) and protein-bound iodine (PBI) were measured in serum obtained from women during the menstrual cycle and the different trimesters of pregnancy and from women taking oral contraceptives for varying periods of time. The free thyroxine index (FTI) was calculated for the pregnant subjects and the free thyroxine factor (FTF) evaluated for all samples studied. Significant deviations from control values in T3 uptake, PBI, FTI and FTF could not be correlated with relatively large changes in the levels of oestrogens. T3 uptake results appeared to reflect changing oestrogenic patterns more closely than the corresponding PBI measurements. Evidence presented suggests that the FTF is preferred to the FTI for clinical use in the diagnosis of thyroid status although further modification to the FTF formula involving PBI and [125I]T3 charcoal uptake measurements may be necessary.


1979 ◽  
Author(s):  
J. Conard ◽  
M.H. Horellou ◽  
B. Cazenave ◽  
M. Samama ◽  
J. R. Zorn ◽  
...  

Antithrombin III (AT III) has been investigated in women before tatting the pill and after 3 months Or more, between the 22nd and the 26th day of the menstrual Cycle. The oral contraceptives consistedinacombination of a progestogen with 30 to 50 ug of oestrogen, or in a progestogen - only pill.AT III was measured by the Hancini method in plasma an serum and the antithrombin activity in serum by the von Kaulla method.The results were obtained from 120 women before taking the pill, 189 taking an oestro-progestagen : containing 50 μg oestrogenin 96 cases, 30 μg in 65 cases, 30 to 40 μg according to the day of the cycle in 28 cases, and 20 women taking a progestagen-only pill.The results show a statistically significant decrease in AT III in plasma and serum, and in antithrombin activity with all the oestroprogestagens. No difference is found between 50 and 30 fig oestrogen content. With the progestogen-only pills, no decrease in AT III is observed.


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