scholarly journals Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

1998 ◽  
Vol 101 (4) ◽  
pp. 847-854 ◽  
Author(s):  
L Iyer ◽  
C D King ◽  
P F Whitington ◽  
M D Green ◽  
S K Roy ◽  
...  
Keyword(s):  
Genetic Predisposition ◽  
Active Metabolite ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Uridine Diphosphate ◽  
Uridine Diphosphate Glucuronosyltransferase

The effects of UDP-sugars, UDP and Mg2+on uridine diphosphate glucuronosyltransferase activity in human liver microsomes

Xenobiotica ◽  
2017 ◽  
Vol 48 (9) ◽  
pp. 882-890 ◽  
Author(s):  
Gurinder Walia ◽  
Alexander D. Smith ◽  
Zoe Riches ◽  
Abby C. Collier ◽  
Michael W. H. Coughtrie
Keyword(s):  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Uridine Diphosphate ◽  
Uridine Diphosphate Glucuronosyltransferase

A Predominate Role of CYP1A2 for the Metabolism of Nabumetone to the Active Metabolite, 6-Methoxy-2-naphthylacetic Acid, in Human Liver Microsomes

2009 ◽  
Vol 37 (5) ◽  
pp. 1017-1024 ◽  
Author(s):  
Miia Turpeinen ◽  
Ute Hofmann ◽  
Kathrin Klein ◽  
Thomas Mürdter ◽  
Matthias Schwab ◽  
...  
Keyword(s):  
Active Metabolite ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Naphthylacetic Acid

scholarly journals The Role of CYP2C8 and CYP2C9 Genotypes in Losartan-Dependent Inhibition of Paclitaxel Metabolism in Human Liver Microsomes

2015 ◽  
Vol 118 (6) ◽  
pp. 408-414 ◽  
Author(s):  
Yuji Mukai ◽  
Asuna Senda ◽  
Takaki Toda ◽  
Erik Eliasson ◽  
Anders Rane ◽  
...  
Keyword(s):  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Dependent Inhibition

Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2

1998 ◽  
Vol 8 (5) ◽  
pp. 423-432 ◽  
Author(s):  
Victoria S. Haritos ◽  
Michael S. Ching ◽  
Hany Ghabrial ◽  
Annette S. Gross ◽  
P??ivi Taavitsainen ◽  
...  
Keyword(s):  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Recombinant Enzymes

scholarly journals Oxidative Metabolism of BDE-99 by Human Liver Microsomes: Predominant Role of CYP2B6

2012 ◽  
Vol 129 (2) ◽  
pp. 280-292 ◽  
Author(s):  
Claudio A. Erratico ◽  
András Szeitz ◽  
Stelvio M. Bandiera
Keyword(s):  
Oxidative Metabolism ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Predominant Role

Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes

2013 ◽  
Vol 42 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Doo-Yeoun Cho ◽  
Soo Hyeon Bae ◽  
Joeng Kee Lee ◽  
Yang Weon Kim ◽  
Bom-Taeck Kim ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Active Metabolite ◽  
Human Liver ◽  
Liver Microsomes ◽  
Selective Inhibition ◽  
Human Liver Microsomes ◽  
Cytochrome P450 2D6 ◽  
P450 2D6

In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: A comparison with human liver microsomes

2008 ◽  
Vol 76 (6) ◽  
pp. 784-795 ◽  
Author(s):  
Luigi Quintieri ◽  
Marianna Fantin ◽  
Pietro Palatini ◽  
Sara De Martin ◽  
Antonio Rosato ◽  
...  
Keyword(s):  
Active Metabolite ◽  
Human Liver ◽  
Anticancer Agent ◽  
Liver Microsomes ◽  
Human Liver Microsomes
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