Journal of Clinical Investigation
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32478
(FIVE YEARS 662)

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500
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Published By American Society For Clinical Investigation

1558-8238, 0021-9738
Latest Documents Most Cited Documents Contributed Authors Related Sources Related Keywords

scholarly journals Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers

2022 ◽  
Author(s):  
Shixiang Sun ◽  
Kristina Brazhnik ◽  
Moonsook Lee ◽  
Alexander Y. Maslov ◽  
Yi Zhang ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Single Cell ◽  
Somatic Mutation ◽  
Single Cell Analysis ◽  
Mammary Epithelial Cells ◽  
Mammary Epithelial ◽  
Cell Analysis ◽  
Mutation Carriers ◽  
Mutation Burden

scholarly journals Boosting NAD+ blunts toll-like receptor-4 induced type-I interferon in control and systemic lupus erythematosus monocytes

2022 ◽  
Author(s):  
Jing Wu ◽  
Komudi Singh ◽  
Amy Lin ◽  
Allison M. Meadows ◽  
Kaiyuan Wu ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Type I Interferon ◽  
Type I ◽  
Toll Like Receptor ◽  
Systemic Lupus ◽  
Toll Like Receptor 4

scholarly journals RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1

2022 ◽  
Author(s):  
Bassam Abu-Libdeh ◽  
Satpal S. Jhujh ◽  
Srijita Dhar ◽  
Joshua A. Sommers ◽  
Arindam Datta ◽  
...  
Keyword(s):  
Genome Instability ◽  
Dna Helicase ◽  
A Genome

scholarly journals Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity

2022 ◽  
Author(s):  
Fiona Bartoli ◽  
Marjolaine Debant ◽  
Eulashini Chuntharpursat-Bon ◽  
Elizabeth L. Evans ◽  
Katie E. Musialowski ◽  
...  
Keyword(s):  
Physical Activity ◽  
Capillary Density

scholarly journals Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation

2022 ◽  
Author(s):  
Vivek D. Gandhi ◽  
Jacqueline-Yvonne Cephus ◽  
Allison E. Norlander ◽  
Nowrin U. Chowdhury ◽  
Jian Zhang ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Airway Inflammation ◽  
Allergic Airway Inflammation ◽  
Receptor Signaling ◽  
Androgen Receptor Signaling ◽  
Suppressive Function

scholarly journals AAV9/MFSD8 gene therapy is effective in preclinical models of neuronal ceroid lipofuscinosis type 7 disease

2022 ◽  
Author(s):  
Xin Chen ◽  
Thomas Dong ◽  
Yuhui Hu ◽  
Frances C. Shaffo ◽  
Nandkishore R. Belur ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Neuronal Ceroid Lipofuscinosis ◽  
Preclinical Models ◽  
Ceroid Lipofuscinosis ◽  
Mfsd8 Gene

scholarly journals ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of non-apoptotic phosphatidylserine

2022 ◽  
Author(s):  
Jun Xu ◽  
Sek Man Su ◽  
Xin Zhang ◽  
Un In Chan ◽  
Ragini Adhav ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mouse Model ◽  
Cancer Metastasis ◽  
Breast Cancer Metastasis

scholarly journals JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

2022 ◽  
Author(s):  
Jui M. Dave ◽  
Raja Chakraborty ◽  
Aglaia Ntokou ◽  
Junichi Saito ◽  
Fatima Z. Saddouk ◽  
...  

scholarly journals Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans

2022 ◽  
Author(s):  
Allison D. Oliva ◽  
Rupali Gupta ◽  
Khalil Issa ◽  
Ralph Abi Hachem ◽  
David W. Jang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Olfactory Loss ◽  
Transcriptional Alterations

scholarly journals LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation

2022 ◽  
Author(s):  
Jamie A. Moore ◽  
Jayna J. Mistry ◽  
Charlotte Hellmich ◽  
Rebecca H. Horton ◽  
Edyta E. Wojtowicz ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Acute Myeloid
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