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Journal of Clinical Investigation
Latest Publications
TOTAL DOCUMENTS
32478
(FIVE YEARS 1805)
H-INDEX
500
(FIVE YEARS 37)
Published By American Society For Clinical Investigation
1558-8238, 0021-9738
Latest Documents
Most Cited Documents
Contributed Authors
Related Sources
Related Keywords
Latest Documents
Most Cited Documents
Contributed Authors
Related Sources
Related Keywords
Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers
Journal of Clinical Investigation
◽
10.1172/jci148113
◽
2022
◽
Author(s):
Shixiang Sun
◽
Kristina Brazhnik
◽
Moonsook Lee
◽
Alexander Y. Maslov
◽
Yi Zhang
◽
...
Keyword(s):
Epithelial Cells
◽
Single Cell
◽
Somatic Mutation
◽
Single Cell Analysis
◽
Mammary Epithelial Cells
◽
Mammary Epithelial
◽
Cell Analysis
◽
Mutation Carriers
◽
Mutation Burden
Download Full-text
Boosting NAD+ blunts toll-like receptor-4 induced type-I interferon in control and systemic lupus erythematosus monocytes
Journal of Clinical Investigation
◽
10.1172/jci139828
◽
2022
◽
Author(s):
Jing Wu
◽
Komudi Singh
◽
Amy Lin
◽
Allison M. Meadows
◽
Kaiyuan Wu
◽
...
Keyword(s):
Systemic Lupus Erythematosus
◽
Lupus Erythematosus
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Type I Interferon
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Type I
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Toll Like Receptor
◽
Systemic Lupus
◽
Toll Like Receptor 4
Download Full-text
RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1
Journal of Clinical Investigation
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10.1172/jci147301
◽
2022
◽
Author(s):
Bassam Abu-Libdeh
◽
Satpal S. Jhujh
◽
Srijita Dhar
◽
Joshua A. Sommers
◽
Arindam Datta
◽
...
Keyword(s):
Genome Instability
◽
Dna Helicase
◽
A Genome
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Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity
Journal of Clinical Investigation
◽
10.1172/jci141775
◽
2022
◽
Author(s):
Fiona Bartoli
◽
Marjolaine Debant
◽
Eulashini Chuntharpursat-Bon
◽
Elizabeth L. Evans
◽
Katie E. Musialowski
◽
...
Keyword(s):
Physical Activity
◽
Capillary Density
Download Full-text
Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation
Journal of Clinical Investigation
◽
10.1172/jci153397
◽
2022
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Author(s):
Vivek D. Gandhi
◽
Jacqueline-Yvonne Cephus
◽
Allison E. Norlander
◽
Nowrin U. Chowdhury
◽
Jian Zhang
◽
...
Keyword(s):
Androgen Receptor
◽
Airway Inflammation
◽
Allergic Airway Inflammation
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Receptor Signaling
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Androgen Receptor Signaling
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Suppressive Function
Download Full-text
AAV9/MFSD8 gene therapy is effective in preclinical models of neuronal ceroid lipofuscinosis type 7 disease
Journal of Clinical Investigation
◽
10.1172/jci146286
◽
2022
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Author(s):
Xin Chen
◽
Thomas Dong
◽
Yuhui Hu
◽
Frances C. Shaffo
◽
Nandkishore R. Belur
◽
...
Keyword(s):
Gene Therapy
◽
Neuronal Ceroid Lipofuscinosis
◽
Preclinical Models
◽
Ceroid Lipofuscinosis
◽
Mfsd8 Gene
Download Full-text
ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of non-apoptotic phosphatidylserine
Journal of Clinical Investigation
◽
10.1172/jci149473
◽
2022
◽
Author(s):
Jun Xu
◽
Sek Man Su
◽
Xin Zhang
◽
Un In Chan
◽
Ragini Adhav
◽
...
Keyword(s):
Breast Cancer
◽
Mouse Model
◽
Cancer Metastasis
◽
Breast Cancer Metastasis
Download Full-text
JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency
Journal of Clinical Investigation
◽
10.1172/jci142338
◽
2022
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Author(s):
Jui M. Dave
◽
Raja Chakraborty
◽
Aglaia Ntokou
◽
Junichi Saito
◽
Fatima Z. Saddouk
◽
...
Download Full-text
Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans
Journal of Clinical Investigation
◽
10.1172/jci155506
◽
2022
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Author(s):
Allison D. Oliva
◽
Rupali Gupta
◽
Khalil Issa
◽
Ralph Abi Hachem
◽
David W. Jang
◽
...
Keyword(s):
Stem Cell
◽
Olfactory Loss
◽
Transcriptional Alterations
Download Full-text
LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation
Journal of Clinical Investigation
◽
10.1172/jci153157
◽
2022
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Author(s):
Jamie A. Moore
◽
Jayna J. Mistry
◽
Charlotte Hellmich
◽
Rebecca H. Horton
◽
Edyta E. Wojtowicz
◽
...
Keyword(s):
Bone Marrow
◽
Acute Myeloid Leukemia
◽
Myeloid Leukemia
◽
Acute Myeloid
Download Full-text
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