Ischaemic Optic Neuropathy and Retinopathy Associated with Acute Pancreatitis

1985 ◽  
Vol 30 (1) ◽  
pp. 46-47 ◽  
Author(s):  
W. G. J. Smith ◽  
J. D. Briggs ◽  
B. J. R. Junor ◽  
J. L. Jay
Keyword(s):  
Renal Failure ◽  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Chronic Renal Failure ◽  
Purtscher’S Retinopathy ◽  
Ischaemic Optic Neuropathy ◽  
Ocular Changes ◽  
Simultaneous Loss ◽  
Optic Discs ◽  
Retinal Haemorrhages

A man with previously undiagnosed chronic renal failure developed acute pancreatitis. He had severe abdominal pain and simultaneous loss of vision. Ophthalmoscopy showed pale, swollen optic discs, soft exudates and superficial retinal haemorrhages similar to that of Purtscher's retinopathy. We suggest that the ocular changes may be due to fat microemboli secondary to acute pancreatitis.

scholarly journals Pancreatic involvement in fatal human leptospirosis: clinical and histopathological features

2003 ◽  
Vol 45 (6) ◽  
pp. 307-313 ◽  
Author(s):  
Elizabeth De Francesco Daher ◽  
Denise Menezes Brunetta ◽  
Geraldo Bezerra da Silva Júnior ◽  
Rainardo Antonio Puster ◽  
Régia Maria do Socorro Vidal Patrocínio
Keyword(s):  
Renal Failure ◽  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Histological Study ◽  
Pulmonary Hemorrhage ◽  
Signs And Symptoms ◽  
Fat Necrosis ◽  
Histopathological Features ◽  
Human Leptospirosis ◽  
Pancreatic Involvement

Hyperamylasemia has been reported in more than 65% of patients with severe leptospirosis, and the true diagnosis of acute pancreatitis is complicated by the fact that renal failure can increase serum amylase levels. Based on these data we retrospectively analyzed the clinical and histopathological features of pancreas involvement in 13 cases of fatal human leptospirosis. The most common signs and symptoms presented at admission were fever, chills, vomiting, myalgia, dehydratation, abdominal pain and diarrhea. Trombocytopenia was evident in 11 patients. Mild increased of AST and ALT levels was seen in 9 patients. Hyperamylasemia was recorded in every patient in whom it was measured, with values above 180 IU/L (3 cases). All patients presented acute renal failure and five have been submitted to dialytic treatment. The main cause of death was acute respiratory failure due to pulmonary hemorrhage. Pancreas fragments were collected for histological study and fat necrosis was the criterion used to classify acute pancreatitis. Histological pancreatic findings were edema, mild inflammatory infiltrate of lymphocytes, hemorrhage, congestion, fat necrosis and calcification. All the patients infected with severe form of leptospirosis who develop abdominal pain should raise the suspect of pancreatic involvement.

scholarly journals Pancreatitis Is a Silent Killer in Peritoneal Dialysis With Difficult Diagnostic Approach

2018 ◽  
Vol 11 ◽  
pp. 117954761876576 ◽  
Author(s):  
Roberta Aliotta ◽  
Luca Zanoli ◽  
Itria Lauretta ◽  
Rosa Giunta ◽  
Silvia Ferrario ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Peritoneal Dialysis ◽  
Pancreatic Pseudocyst ◽  
Rate Condition ◽  
Severe Pancreatitis ◽  
Left Shift ◽  
Fungal Sepsis ◽  
Candida Peritonitis

Until 2018, 236 cases of acute pancreatitis have been reported in patients who underwent peritoneal dialysis. Here, we presented a patient with double renal transplantation with chronic renal failure, under renal replacement therapy by peritoneal dialysis, who developed acute pancreatitis with abdominal pain, nausea, vomiting, leukocytosis with neutrophil left shift which is complicated by pancreatic pseudocyst, candida peritonitis, fungal sepsis, overlapping of Acinetobacter baumannii sepsis, and pneumonitis. After the percutaneous cystogastrostomy drainage of pancreatic pseudocyst, changes from peritoneal dialysis to hemodialysis, various thoracentesis, and polyantibiotics therapy, the resolution of the sepsis state was seen. The particular aspect of our case is the various comorbidity risks, severe pancreatitis associated with candida and A baumannii sepsis, and treatment strategy that lead to heal this kind of the high mortality rate condition.

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