Doppler Echocardiographic Assessment of Left Ventricular Diastolic Function in Patients with Primary Lung Cancer Treated with Doxorubicin

1988 ◽  
Vol 74 (6) ◽  
pp. 725-729 ◽  
Author(s):  
Stefania Maione ◽  
Anna Giunta ◽  
Bernardino Tuccillo ◽  
Renato Biagini ◽  
Paola Del Rosso ◽  
...  

Eighteen patients were examined by Doppler echocardiography before and after treatment with doxorubicin (DXR). Early left ventricular filling rate decreased from 66±15 to 51±10 cm/sec whereas late filling rate increased from 48±12 to 61±9 cm/sec (p < 0.05) with inversion of the E/A ratio suggesting an impairment of left ventricular diastolic function; conversely no significant changes were found in systolic function indexes. These results suggest that follow-up of patients treated with DXR must include left ventricular diastolic function studies. Doppler echocardiography can be successfully used to detect the presence of diastolic abnormalities.

2016 ◽  
Vol 72 (1) ◽  
Author(s):  
Enrico Vizzardi ◽  
Pompilio Faggiano ◽  
Ermanna Chiari ◽  
Diego Maffeo ◽  
Silvia Frattini ◽  
...  

The study of diastolic function by Doppler-echocardiography is complex and demanding. The cardiologist/echocardiographist must have a systematic approach to the study of left ventricular diastolic function, not only based on the Doppler index, but integrating Doppler patterns with other echo-parameters (chamber dimensions, wall thicknesses, systolic function, valve function and morphology) and clinical information. A rational interpretation of clinical and instrumental data can allow a correct diagnosis, which is essential for clinical decision-making.


2007 ◽  
Vol 3 (1-2) ◽  
pp. 182618680700300 ◽  
Author(s):  
Pompilio Faggiano ◽  
Enrico Vizzardi ◽  
Emanuela Pulcini ◽  
Diego Maffeo ◽  
Francesco Fracassi ◽  
...  

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