Chemical Partitioning into Powdered Human Stratum Corneum: A Useful In Vitro Model for Studying Interaction of Chemicals and Human Skin

2005 ◽  
pp. 327-338
Keyword(s):  
Stratum Corneum ◽  
Human Skin ◽  
In Vitro Model ◽  
Chemical Partitioning ◽  
Human Stratum Corneum ◽  
Vitro Model

scholarly journals An In vitro Model for Bacterial Growth on Human Stratum Corneum

2016 ◽  
Vol 96 (7) ◽  
pp. 873-879 ◽  
Author(s):  
D Krieken ◽  
T Ederveen ◽  
S Hijum ◽  
P Jansen ◽  
W Melchers ◽  
...  
Keyword(s):  
Stratum Corneum ◽  
Bacterial Growth ◽  
In Vitro Model ◽  
Human Stratum Corneum ◽  
Vitro Model

Human Skin Binding and Absorption of Contaminants from Ground and Surface Water During Swimming and Bathing

1989 ◽  
Vol 8 (5) ◽  
pp. 853-859 ◽  
Author(s):  
Ronald C. Wester ◽  
Howard I. Maibach
Keyword(s):  
Surface Water ◽  
Stratum Corneum ◽  
Human Skin ◽  
The Body ◽  
Water Soluble ◽  
Exposure Effect ◽  
Human Stratum Corneum ◽  
Water Dilution

Contaminants exist in ground and surface water. Human skin has the capacity to bind and then absorb these contaminants into the body during swimming and bathing. Powdered human stratum corneum will bind both lipid-soluble (alachlor, polychlorinated biphenyls [PCBs], benzene) and water-soluble (nitroaniline) chemicals. In vitro (human skin) and in vivo (Rhesus monkey) studies show that these chemicals readily distribute into skin, and then some of the chemical is absorbed into the body. Linearity in binding and absorption exists for nitroaniline over a 10-fold concentration range. Multiple exposure to benzene is at least cumulative. Binding and absorption can be significant for exposures as short as 30 min, and will increase with time. Absorption with water dilution increased for alachlor, but not for dinoseb. Soap reversed the partitioning of alachlor between human stratum corneum and water. The PCBs could be removed from skin by soap and water (70% efficiency) for up to 3 h and then decontamination potential decreased, due to continuing skin absorption. The model in vitro and in vivo systems used should permit easy estimation of this area of extensive human exposure effect on risk assessment.

scholarly journals 908 Bioengineering a novel in vitro model to study ageing in human skin

2019 ◽  
Vol 139 (5) ◽  
pp. S157
Author(s):  
L.F. Costello ◽  
N. Fullard ◽  
M. Roger ◽  
B. Hulette ◽  
D.S. Hill ◽  
...  
Keyword(s):  
Human Skin ◽  
In Vitro Model ◽  
Vitro Model

scholarly journals Evaluation of cryogen spray cooling exposure on in vitro model human skin

2004 ◽  
Vol 34 (2) ◽  
pp. 146-154 ◽  
Author(s):  
Bunsho Kao ◽  
Kristen M. Kelly ◽  
Guillermo Aguilar ◽  
Yoshiaki Hosaka ◽  
Ronald J. Barr ◽  
...  
Keyword(s):  
Human Skin ◽  
In Vitro Model ◽  
Spray Cooling ◽  
Cryogen Spray Cooling ◽  
Vitro Model

Impact of resveratrol analogues on a 3D in vitro model of human skin

2017 ◽  
Vol 94 ◽  
pp. 116-117
Author(s):  
Fabian Nagelreiter ◽  
Regina Weinmüllner ◽  
Thomas Erker ◽  
Johannes Grillari ◽  
Markus Schosserer
Keyword(s):  
Human Skin ◽  
In Vitro Model ◽  
3D In Vitro Model ◽  
Resveratrol Analogues ◽  
Vitro Model

In vitro model for decontamination of human skin: Formaldehyde

2007 ◽  
Vol 45 (4) ◽  
pp. 618-621 ◽  
Author(s):  
H. Zhai ◽  
S. Barbadillo ◽  
X. Hui ◽  
H.I. Maibach
Keyword(s):  
Human Skin ◽  
In Vitro Model ◽  
Vitro Model
Sign in / Sign up

Export Citation Format

Share Document