Intra-Axonal Transport of Cytoskeletal Proteins

2018 ◽  
pp. 69-80
Author(s):  
Masanori Kurokawa
Keyword(s):  
Axonal Transport ◽  
Cytoskeletal Proteins

Experimental diabetic neuropathy. Effect of ganglioside treatment on axonal transport of cytoskeletal proteins

Diabetes ◽  
1992 ◽  
Vol 41 (7) ◽  
pp. 866-871 ◽  
Author(s):  
B. Figliomeni ◽  
B. Bacci ◽  
C. Panozzo ◽  
F. Fogarolo ◽  
C. Triban ◽  
...  
Keyword(s):  
Diabetic Neuropathy ◽  
Axonal Transport ◽  
Cytoskeletal Proteins ◽  
Experimental Diabetic Neuropathy

Translocation of the neuronal cytoskeleton and axonal locomotion

1982 ◽  
Vol 299 (1095) ◽  
pp. 313-327 ◽  
Keyword(s):  
Plasma Membrane ◽  
Axonal Transport ◽  
Cell Body ◽  
Cytoskeletal Proteins ◽  
The Other ◽  
Current Understanding ◽  
Axonal Elongation ◽  
Neuronal Cytoskeleton ◽  
Other Hand ◽  
Neuron Cell Body

Recent studies of axonal transport indicate that cytoskeletal proteins are assembled into polymers in the neuron cell body and that these polymers move from the cell body toward the end of the axon. On the other hand, membranous elements appear to be inserted into the axonal plasma membrane preferentially at the end of the axon. These new observations are explored in relation to our current understanding of axonal elongation.

Axonopathy-Inducing 1,2-Diacetylbenzene Forms Adducts with Motor and Cytoskeletal Proteins Required for Axonal Transport

2007 ◽  
Vol 32 (12) ◽  
pp. 2152-2159 ◽  
Author(s):  
Mohammad I. Sabri ◽  
Seyed B. Hashemi ◽  
Michael R. Lasarev ◽  
Peter S. Spencer
Keyword(s):  
Axonal Transport ◽  
Cytoskeletal Proteins

Experimental Diabetic Neuropathy: Effect of Ganglioside Treatment on Axonal Transport of Cytoskeletal Proteins

Diabetes ◽  
1992 ◽  
Vol 41 (7) ◽  
pp. 866-871 ◽  
Author(s):  
B. Figliomeni ◽  
B. Bacci ◽  
C. Panozzo ◽  
F. Fogarolo ◽  
C. Triban ◽  
...  
Keyword(s):  
Diabetic Neuropathy ◽  
Axonal Transport ◽  
Cytoskeletal Proteins ◽  
Experimental Diabetic Neuropathy

Altered Axonal Transport of Cytoskeletal Proteins in the Mutant Diabetic Mouse

1985 ◽  
Vol 45 (3) ◽  
pp. 860-868 ◽  
Author(s):  
M. Vitadello ◽  
G. Filliatreau ◽  
J. L. Dupont ◽  
R. Hassig ◽  
A. Gorio ◽  
...  
Keyword(s):  
Axonal Transport ◽  
Diabetic Mouse ◽  
Cytoskeletal Proteins

Slow Axonal Transport Impairment of Cytoskeletal Proteins in Streptozociti-Induced Diabetic Neuropathy

1989 ◽  
Vol 53 (4) ◽  
pp. 1261-1267 ◽  
Author(s):  
P. Macioce ◽  
G. Filliatreau ◽  
B. Figliomeni ◽  
R. Hassig ◽  
Jean Thiéry ◽  
...  
Keyword(s):  
Diabetic Neuropathy ◽  
Axonal Transport ◽  
Cytoskeletal Proteins ◽  
Slow Axonal Transport

scholarly journals Fast axonal transport of foreign synaptic vesicles in squid axoplasm.

1985 ◽  
Vol 101 (2) ◽  
pp. 568-572 ◽  
Author(s):  
T A Schroer ◽  
S T Brady ◽  
R B Kelly
Keyword(s):  
Axonal Transport ◽  
Synaptic Vesicles ◽  
Electric Fish ◽  
Cytoskeletal Proteins ◽  
Protein Component ◽  
Squid Axon ◽  
Fast Axonal Transport ◽  
Intracellular Organelles ◽  
Cellular Cytoskeleton

Translocation of intracellular organelles requires interaction with the cellular cytoskeleton, but the membrane and cytoskeletal proteins involved in movement are unknown. Here we show that highly purified synaptic vesicles from electric fish added to extruded squid axoplasm can show ATP-dependent movement. The movement is indistinguishable from that of endogenous vesicles and has a slight preference for the orthograde direction. In the presence of a nonhydrolyzable ATP analog, the synaptic vesicles bind to axoplasmic fibers but do not move. Elastase treatment of vesicles inhibits both binding and movement. We conclude that a protein component on the surface of cholinergic synaptic vesicles from electric fish is conserved during evolution and so can be recognized by the organelle-translocating machinery of the squid axon, resulting in ATP-dependent movement. Synaptic vesicles apparently retain the capacity for fast axonal transport, even after they reach their intracellular destination.

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