scholarly journals Ion channel noise shapes the electrical activity of endocrine cells

2020 ◽  
Vol 16 (4) ◽  
pp. e1007769 ◽  
Author(s):  
David M. Richards ◽  
Jamie J. Walker ◽  
Joel Tabak
2015 ◽  
Vol 4 (4) ◽  
pp. 364
Author(s):  
Ahmed Mahmood Khudhur ◽  
Ahmed N Abdalla ◽  
Jasni Mohamad Zain ◽  
Hai Tao

<p class="MsoNormal" style="text-align: justify; text-justify: inter-ideograph;"><span style="font-size: 10.0pt;">In recent years, it has been argued and experimentally shown that ion channel noise in neurons can have profound effects on the neuron’s dynamical behavior. Most profoundly, ion channel noise was seen to be able to cause spontaneous firing and stochastic resonance. It has been recently found that a non-trivially persistent cross correlation takes place between the transmembrane voltage fluctuations and the component of open channel fluctuations attributed to gate multiplicity. This non-trivial phenomenon was found to play a major augmentative role for the elevation of excitability and spontaneous firing in the small size cell. In addition, the same phenomenon was found to significantly enhance the spike coherence. In this paper, statistics of the coefficient of variation, to be obtained from the colored stochastic Hodgkin-Huxley equations using voltage clamps techniqueswill be studied. The simulation result shows the coefficient of variation; enhance the agreement with the microscopeinthe case of the noisy currents.</span></p>


2005 ◽  
Vol 15 (12) ◽  
pp. 1143-1149 ◽  
Author(s):  
A. Aldo Faisal ◽  
John A. White ◽  
Simon B. Laughlin

2019 ◽  
Vol 8 (3) ◽  
pp. 10
Author(s):  
Renas R Asaad

Recently, theoretical arguments, numerical simulation and experiments shown that ion channel noise in neurons can have deep impact on the behavior of the neuron's dynamical when there is a limited size for the membrane space. It can be create different models of Linaro al equations by using stochastic differential equations to find the impacts of ion channel noise, and it has been analytically put forward the Güler model. More recently, Güler has discussed that in small neurons the rate functions for the closing and opening of gates are under the effect of the noise. In this research, the investigation of dynamics neurons are determined with noise rate functions. The exact Markov simulations will be employ during the investigation with above analytical models. Comparatively, the results will be presented from these models. The research aims to show more details on the phenomenon recently outlined by Güler.


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