1226 Under-Utilization of Proton Pump Inhibitors in the Prevention of NSAID-Related Peptic Ulcer Disease in the Elderly

2019 ◽  
Vol 114 (1) ◽  
pp. S684-S684
Author(s):  
Ahmad M. Al-Taee ◽  
Elie Ghoulam ◽  
Preston Lee ◽  
Robert Sbertoli ◽  
Christine Hachem
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
The Elderly ◽  
Ulcer Disease

scholarly journals Proton Pump Inhibition is a Feasible Primary Alternative to Surgery and Balloon Dilatation in Adult Peptic Pyloric Stenosis (APS): Report of Six Consecutive Cases

2006 ◽  
Vol 88 (2) ◽  
pp. 174-175 ◽  
Author(s):  
J Shabbir ◽  
S Durrani ◽  
PF Ridgway ◽  
K Mealy
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Pyloric Stenosis ◽  
Median Duration ◽  
Oral Treatment ◽  
Duration Of Symptoms ◽  
Ulcer Disease ◽  
Proton Pump Inhibition

INTRODUCTION Surgery has been the gold standard in the treatment of adult pyloric stenosis (APS). The introduction of proton pump inhibitors (PPIs) in 1989 revolutionised the treatment of peptic ulcer disease and its complications. PATIENTS AND METHODS We carried out a prospective study to evaluate the effectiveness of PPIs as an alternative to surgery for treatment of APS. Six consecutive patients admitted with a diagnosis of adult peptic pyloric stenosis between November 1999 and August 2002 were studied. The diagnosis was confirmed with endoscopy. All patients were commenced on a twice-daily dose of intravenous PPI. This was changed to oral treatment after 2 days. Main outcome measures evaluated were resolution of symptoms on PPIs and failure of medical therapy. RESULTS There were five females and one male. Median age at diagnosis was 72 years (range, 30–90 years). Median duration of symptoms was 2 weeks (range, 1–5 weeks). Of the patients, five had a history of peptic ulcer disease. Complete resolution was achieved in 5 patients (83%). Median duration for resolution of symptoms was 9 days (range, 5–14 days). All patients were changed to oral PPIs after 2 days. One patient did not respond to oral therapy and required surgical intervention (pyloroplasty). Median follow-up was 26 months (range, 6–48 months). There was no recurrence of symptoms. All patients were discharged on low-dose PPI. CONCLUSIONS This study supports the view that proton pump inhibitors are a safe and feasible alternative to surgery in adult pyloric stenosis secondary to peptic ulcer disease.

Proton pump inhibitors and recurrent bleeding in peptic ulcer disease

2008 ◽  
Vol 23 ◽  
pp. S237-S241 ◽  
Author(s):  
Akihiro Tajima ◽  
Kazuhito Koizumi ◽  
Kazuyoshi Suzuki ◽  
Naoko Higashi ◽  
Morio Takahashi ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Recurrent Bleeding ◽  
Ulcer Disease

scholarly journals Proton pump inhibitors, purple gastric juice and peptic ulcer disease

QJM ◽  
2016 ◽  
Vol 110 (1) ◽  
pp. 43-43
Author(s):  
Y.-C. Chang ◽  
P.-J. Hsiao ◽  
K.-L. Wu ◽  
C.-J. Hsiao
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Gastric Juice ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Ulcer Disease

Peptic Ulcer Disease in the Elderly

2018 ◽  
pp. 143-146
Author(s):  
Nages Nagaratnam ◽  
Kujan Nagaratnam ◽  
Gary Cheuk
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
The Elderly ◽  
Ulcer Disease
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