scholarly journals Prenatal diagnosis and therapy of fetal heart rate anomalies: With a contribution on the placental transfer of Verapamil

1980 ◽  
Vol 8 (4) ◽  
pp. 203-208 ◽  
Author(s):  
F. Wolff ◽  
K. H. Breuker ◽  
K. H. Schlensker ◽  
A. Bolte
1984 ◽  
Vol 62 (12) ◽  
pp. 1435-1439 ◽  
Author(s):  
M. E. Cumming ◽  
B. Y. Ong ◽  
J. G. Wade ◽  
D. S. Sitar

The disposition and cardiovascular effects of ethanol were studied in near-term pregnant sheep and their fetuses after intravenous infusions either to the mother or the fetus. Placental transfer of ethanol from mother to fetus was rapid, but transfer from the fetal to maternal circulation was impaired when ethanol was administered directly to the fetus. Plasma clearance of ethanol was similar from the mother and fetus in utero. In the maternal infusion experiments, both maternal and fetal heart rate increased with plasma ethanol concentration. However, in the fetal infusion experiments, fetal heart rate was inversely related to plasma ethanol concentrations while maternal mean arterial blood pressure increased with maternal plasma ethanol concentration. Further studies in neonatal lambs are needed to determine if ethanol has adverse effects on hemodynamics when the neonate is separated from its protective intrauterine environment.


1998 ◽  
Vol 5 (1) ◽  
pp. 168A-168A
Author(s):  
J WILSON ◽  
C LOWERY ◽  
P MURPHY ◽  
W RUSSELL ◽  
R WALLS

1996 ◽  
Author(s):  
James A. McCubbin ◽  
Erma J. Lawson ◽  
Jeffrey J. Sherman ◽  
Jane A. Norton

Sign in / Sign up

Export Citation Format

Share Document