Adrenal insufficiency due to both hemorrhage and thrombosis related with primary antiphospholipid syndrome

2017 ◽  
Author(s):  
Buket Bicer ◽  
Pinar Sisman ◽  
Soner Cander ◽  
Gul Ozen Oz ◽  
Canan Ersoy
Keyword(s):  
Adrenal Insufficiency ◽  
Antiphospholipid Syndrome ◽  
Primary Antiphospholipid Syndrome

scholarly journals Acute adrenal failure as the heralding symptom of primary antiphospholipid syndrome: report of a case and review of the literature

2005 ◽  
Vol 153 (4) ◽  
pp. 507-514 ◽  
Author(s):  
Fabio Presotto ◽  
Francesca Fornasini ◽  
Corrado Betterle ◽  
Giovanni Federspil ◽  
Marco Rossato
Keyword(s):  
Abdominal Pain ◽  
Adrenal Insufficiency ◽  
Antiphospholipid Syndrome ◽  
Great Majority ◽  
Primary Antiphospholipid Syndrome ◽  
Adrenal Failure ◽  
Adrenal Haemorrhage ◽  
Morphological Findings ◽  
Acute Adrenal Insufficiency ◽  
Acute Adrenal Failure

Acute adrenal failure is a potentially fatal condition if overlooked. Occasionally, acute adrenal insufficiency may ensue from bilateral adrenal haemorrhage in patients with known antiphospholipid syndrome (APS). APS is characterized by recurrent arterial and venous thrombosis, pregnancy complications and detection of autoantibodies to phospholipids. This syndrome may be associated with non-organ specific diseases (e.g. connective tissue disorders) or with malignancies, but it may also appear in isolated form (primary APS). In a very few cases the heralding manifestation is given by adrenal failure. We report here a 63-year-old man presenting with acute adrenal insufficiency as the opening clinical manifestation of an APS. We also carried out a computer-aided search of the literature to identify all cases of primary adrenal failure as the first-recognized expression of a primary APS, a condition that not so infrequently may be tackled by endocrinologists. 20 patients fulfilled the inclusion criteria. The great majority of them were males (75%) with a mean age of 42 years. Abdominal pain was present in 14 patients, followed by fever (13 patients) and hypotension (12 patients). The main morphological findings by computed tomography or magnetic resonance were consistent with bilateral adrenal haemorrhage in 11 patients. Lupus anticoagulant was present in all of the 19 tested patients. Our observations emphasize the importance in the assessment of clotting times, and possibly of antiphospholipid antibodies, in all patients with diagnosis of rapidly progressive adrenal failure and concurrent abdominal pain.

scholarly journals Definitive Adrenal Insufficiency Due to Bilateral Adrenal Hemorrhage and Primary Antiphospholipid Syndrome

1998 ◽  
Vol 83 (5) ◽  
pp. 1437-1439 ◽  
Author(s):  
Philippe Caron ◽  
Marie-Hélène Chabannier ◽  
Jean-Pierre Cambus ◽  
Françoise Fortenfant ◽  
Philippe Otal ◽  
...  
Keyword(s):  
Adrenal Insufficiency ◽  
Antiphospholipid Syndrome ◽  
Adrenal Hemorrhage ◽  
Primary Antiphospholipid Syndrome ◽  
Bilateral Adrenal Hemorrhage

Adrenal Insufficiency After Laparoscopic Hysterectomy in a Patient With Primary Antiphospholipid Syndrome

2008 ◽  
Vol 111 (2, Part 2) ◽  
pp. 495-498 ◽  
Author(s):  
E Dierking ◽  
R Gogoi ◽  
S Adamcik ◽  
L W. Greene ◽  
J P. Curtin
Keyword(s):  
Adrenal Insufficiency ◽  
Antiphospholipid Syndrome ◽  
Laparoscopic Hysterectomy ◽  
Primary Antiphospholipid Syndrome

Primary Antiphospholipid Syndrome: An Unusual Cause of Adrenal Insufficiency

2001 ◽  
Vol 56 (3-4) ◽  
pp. 140-144 ◽  
Author(s):  
E. Böber ◽  
A. Kovanlıkaya ◽  
A. Büyükgebiz
Keyword(s):  
Adrenal Insufficiency ◽  
Antiphospholipid Syndrome ◽  
Primary Antiphospholipid Syndrome

Preeclampsia in primary antiphospholipid syndrome is associated with fetal losses and limb ischemia

2021 ◽  
Author(s):  
Jozélio Freire de Carvalho ◽  
Maria Betania Pereira Toralles ◽  
Maria Isabel Figueiredo Sousa ◽  
Thelma Larocca Skare
Keyword(s):  
Antiphospholipid Syndrome ◽  
Limb Ischemia ◽  
Primary Antiphospholipid Syndrome
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