Serum irisin levels in chronic open-angle glaucoma

2019 ◽  
Vol 9 (6) ◽  
pp. 159-163
Author(s):  
Burak Turgut ◽  
Kadir Mercan ◽  
Nevin Ilhan ◽  
Onur Çatak
1995 ◽  
Vol 5 (3) ◽  
pp. 172-176 ◽  
Author(s):  
S.K. Akafo ◽  
J.R. Thompson ◽  
A.R. Rosenthal

The intraocular pressure (IOP) lowering efficacy of once-daily levobunolol 0.5% was compared with timolol 0.5% twice-daily and timolol 0.5% once-daily in 20 chronic open angle glaucoma and 5 ocular hypertensive patients. The design used was a randomised double blind cross-over trial with three periods each of 8 weeks separated by 2 weeks of no treatment. We found that following levobunolol a two week washout was not sufficient for the IOP to return to its original baseline level suggesting that levobunolol is a longer acting drug than timolol. Adjusting for this carryover effect, we found no significant difference in the IOP lowering effect among the three regimes (p=0.53). Reduced cost, less ocular discomfort and better compliance are the main potential advantages of the once daily treatments.


1991 ◽  
Vol 111 (4) ◽  
pp. 491-500 ◽  
Author(s):  
Colm O'Brien ◽  
Bernard Schwartz ◽  
Takenori Takamoto ◽  
Da Ching Wu

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