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2022 ◽  
Vol 28 (1) ◽  
pp. 68-71
Xiaowei He

ABSTRACT Introduction: The mental health of college students is getting more and more attention from society. Physical exercise as a means of psychotherapy and mental health has become common at home and abroad. Objective: We explore the effect of prescribing physical exercise in the treatment of depression in college students. Methods: College students who had been diagnosed with depression were randomly divided into an observation group and a control group, each with 18 patients. The control group received drug treatment. The observation group received sports therapy in addition to drug therapy. Results: There was a statistically significant difference in HAMD scores between the observation and control groups in the first week (P<0.01). Conclusions: Exercise can play a role in treating depression patients rapidly, safely, and efficiently. Level of evidence II; Therapeutic studies - investigation of treatment results.

2022 ◽  
Vol 13 (1) ◽  
pp. 086-091
Nofita Fachryandini ◽  
Shabrina Nur Imanina ◽  
Ayurveda Zaynabila Heriqbaldi ◽  
Widati Fatmaningrum

Introduction: Taro village has a higher risk of gathering the people since it is one of the most popular tourism sectors in Bali hence increasing the potential to spread coronavirus disease 2019 (COVID-19). The level of knowledge plays an important role in determining whether the society is ready to implement the health protocols or not. This community service aims to evaluate the level of knowledge regarding COVID-19 health protocols in the tourism sector in the Taro village. Method: This research was conducted using a quasi-experimental one-group pretest-posttest design in Taro village, Bali. Respondents filled out the questionnaire before and after counseling. The questionnaire consisted of 10 items of knowledge. The participants were Taro’s residents who met inclusion and exclusion criteria. A total of 31 respondents were taken. The data were tested for normality with the Kolmogorov-Smirnov test and analyzed with paired T-test using the IBM SPSS statistics version 25. Significance was determined at a 5% level (P-value ≤0.05). Results: A total of 31 valid filled-questionnaires were collected. In general, Taro’s residents’ knowledge regarding COVID-19 health protocol in the tourism sector was sufficient, but some topics are still insufficient. The mean score before counseling was 79,03 ± 1,340 while the mean score after counseling was 86,13 ± 1,366. There was a significant difference (p<0,05) on level of knowledge (p=0,000) before and after counseling. Conclusion: There was a significant difference in the level of knowledge of Taro village’s residents toward COVID-19 health protocols in the tourism sector before and after counseling.

2022 ◽  
Vol 12 (5) ◽  
pp. 907-913
Liyan Zhong ◽  
Yi Yi ◽  
Qian Liu ◽  
Yan Peng

This study intends to discuss the mechanism of MTH1 inhibitor (TH588) in the biological activity of ovarian carcinoma cells. A2780 and SKOV-3 cells were treated with different concentrations of TH588 and assigned into AT group (control), BT group (8 μmol/L TH588), CT group (16 μmol/L), DT group (32 μmol/L), ET group (64 μmol/L) and FT group (128 μmol/L) followed by measuring level of Bcl-2 and Bax by Western blot and PCR, and cell biological activities by MTT, FCM and Transwell chamber assay. The cell proliferative rate was not affected in AT group, but was lower in other groups in a reverse dose-dependent manner. There was significant difference on apoptotic rate and cell invasion among groups with increased apoptosis and reduce invasion after TH588 treatment. FT group showed lowest expression of Bcl-2 and Bax compared to other groups. In conclusion, the biological activity of A2780/SKOV3 cells could be reduced by MTH1 inhibitor which was probably through regulation of Bax and Bcl-2 expression.

2022 ◽  
Vol 13 (1) ◽  
pp. 250-254
Maftuhatur Rizkiyah Putri ◽  
Almira Disya Salsabil ◽  
I Made Agus Dwipayana ◽  
Widati Fatmaningrum

Introduction: The COVID-19 pandemic has harmed various fields, and people's activities cannot run as usual. Prevention of the transmission of COVID-19 is very important to be applied in everyday life. Washing hands with soap or hand sanitizer is easy and inexpensive prevention to do, but there are still many people who are wrong in practicing it. This needs to be done more counseling and education to the community in order to increase public knowledge about handwashing and hand sanitizer. Method: This research is an analytic study with a research design using a one-group pretest-posttest design. Using 31 respondents from Taro villagers who attended the counseling. Data analysis using Paired Sample T-test and Kolmogorov-Smirnov Test for Normality Test. Result: The average value of knowledge before counseling is 53.8710 while the value after counseling is 82.9677. Paired Sample T-test and obtained a significance value of 0.000 so that a significant difference was found (<0.005) between the values before and after counseling. Conclusion: There is a significant difference in the level of knowledge before and after handwashing and hand sanitizer counseling.

2022 ◽  
Vol 13 (1) ◽  
pp. 197-202
Intan Permata Sari ◽  
Fauziah Adhima ◽  
Ghivari Zuhal Fahmi ◽  
Ramidha Syaharani ◽  
Widati Fatmaningrum

Introduction: As of 31st December 2021, there have been 4,262,540 confirmed cases of COVID-19, including 144,088 death cases in Indonesia. COVID-19 pandemic has affected the nutrition aspect, as an increasing number of undernutrition children also increases risk of obesity. Our group conducts webinars with the purpose of increasing public knowledge and awareness regarding general well-being: importance of adequate nutrition to increase immunity in the COVID-19 pandemic. The purpose of the study is to examine webinar participants' knowledge before and after webinar. Method: The webinar conducted through a zoom meeting for 2 hours consists of 1 hour education and 1 hour question and answer session. The participants asked to fill a pretest before the webinar session and posttest after the webinar session. The results were statistically examined to determine the difference between pretest and posttest score. Results: The webinar participant’s demographic characteristics were dominated by 17-45 years old age group, high school graduates, and female participants. There is a significant difference (p<0.05) between pre and post-test score evaluated using Wilcoxon signed-rank test. After the webinar, there is a decreased number of participants with low-level nutritional knowledge from 31 to 23 participants. Conclusion: There is an increase in knowledge about the importance of adequate nutrition to increase immunity in the COVID-19 pandemic from pre and post-test data. Thus, this webinar contributes to providing knowledge to participants in supporting the strengthening of socialization of adequate nutrition during COVID-19 pandemic.

Ahmed Abdelfattah Bayomy Nofal ◽  
Mohammad Waheed El-Anwar

AbstractFrontal recess cells have many types with different sizes, arrangement, and extend. It plays an important role in successful functional endoscopic sinus surgery (FESS) as most causes of failure are related to it. Outline the prevalence of the frontal recess cells, pathological incidence of each cell regarding to frontal sinus pathology. Prospective study on 100 consecutive patients (200 sides) complaining from nasal and sinus symptoms which did not respond to medical management and indicated for FESS. Anterior group was infected in 30.8%; agger nasi cell (ANC) present in 97% (25.8% infected, 74.2% not infected), supra agger cell (SAC) present in 48% (39.6% infected, 60.4% not infected), supra agger frontal cell (SAFC) present in 11% (36.4% infected, 63.6% not infected). Posterior group was infected in 24.8%; supra bulla cell (SBC) present in 72% (30.6% infected, 69.4% not infected), supra bulla frontal cell (SBFC) present in 23% (17.4% infected, 82.6% not infected), supra orbital ethmoid cell (SOEC) present in 42% of cases (19% infected, 81% not infected). Medial group [frontal septal cell (FSC)] was present in 21% (33.3% infected, 66.7% not infected). FSC, SAC, SAFC, and SBC showed high infection rate in association with infected frontal sinus, while, the SOEC, ANC, and SBFC did not have such high infection rate. Frontal recess cells show no difference in their prevalence either if the frontal sinus infected or not, however their infection rate show significant difference.

2022 ◽  
Vol 25 (3) ◽  
Magdalena Malczewska ◽  
Edyta Janus

Introduction: There are many difficulties connected with caring for an elderly person sufferring dementia. Symptoms such as aggression or apathy, as well as the progressive nature of the disorder, affect the attitude of both home and institutional caregivers towards the people for whom they care. An important element related to the provision of care is the relationship between a senior with dementia and those who provide the care (home and institutional caregivers). The aim of the article is to characterise and compare these relations. Material and methods: The study comprised 124 participants, 57 professional caregivers and 67 home carers. Two standardised questionnaires were used: the Neuropsychiatric Inventory Questionnaire (NPI-Q) and the Quality of Carer-Patient Relationship - QCPR Questionnaire. Additionally, the respondents provided socio-demographic data. The study was conducted via electronic media in the first quarter of 2021. Results: It was found that there is a significant difference in the relationship between home and institutional caregivers, with their charges in the dimension of "warmth and attachment" (measured by QCPR). People providing professional care have significantly higher scores in this area. There was also a significant difference between scores in the 'no conflict and criticism' dimension (measured by QCPR) for home and professional caregivers. Institutional caregivers, in relation to their care recipients, have a higher level of this indicator than home caregivers. Conclusions: Relationships between seniors with dementia and institutional or home carers differ with regard to some issues. The differences in relationships with seniors suffering dementia may be due to the time spent caring for this person and the caregiver's response to symptoms of dementia.

2022 ◽  
Vol 19 (1) ◽  
pp. 5-8
Mohan Belbase ◽  
Jyoti Adhikari

Introduction: Obsessive compulsive disorder is a common, chronic and disabling disorder marked by obsessions and/or compulsions. This study tries to find the demographic profiles, severity and response of antiobsessive drugs in young and adult patients with obsessive compulsive disorder. Aims: To study the socio-demographic profile, severity and treatment response to commonly used antiobsessive medications in male and female, and young and adults. Methods: This is a hospital based experimental study done in patients attending to psychiatry out-patient department over one year from February 2020 to January 2021.  Diagnosis of obsessive compulsive disorder was made based on International Classification of Disease- 10 criteria for research. Yale-Brown obsessive compulsive scale check list (adult and children) was applied in those patients and recorded accordingly on baseline (week 0) and patients were treated with specific serotonin reuptake inhibitors or tricyclic antidepressants in therapeutic doses for 6 weeks. On follow up at week 6, they were again reassessed and the scores were recorded and analyzed. Results: Among the total study subject (N-52), 26(50 %) were male and 26(50 %) were females. Patients in age bracket 20-29 is the most common age group representing 18(34.6 %). Mean age of patients is 30.36±11.93 years (28.65±9.80 in male and 32.04±13.73 in female). Severe form of obsessive compulsive disorder was the most common type that represent 33(63.5%) followed by moderate 16(30.8%) and extreme 3(5.7%). There is a difference of treatment response of antiobsessive therapy in male and female with statistical significance (p= 0.039). Conclusion: This study shows that obsessive compulsive disorder is most commonly found in 20-29 age group and the severe type is the most common. There is a significant difference in treatment response of antiobsessive therapy in male and female.

Shivakumar A H ◽  
Sumana R ◽  
Maheshkrishna B G ◽  
Yasodai R

Determination of sex using Skeletal remains is a challenging topic with so many tools being used for the sex determination of Skull in this study. The interstyloid process distance were studied in 64 Skulls and were tabulated and analysed. There is a significant difference between the distance in Female skull and Male skull, the former being lesser compared to the later. Further study in this regard may help using Interstyloid process distance as a important tool in identification of the Sex of the Skull.

2022 ◽  
Vol 8 (1) ◽  
pp. 1-6
Reshma Shireesha ◽  
Obulesu Obulesu

Background: Aim: To assess the effect of exercise on body composition in obese and overweight. Methods: A total of seventy- two overweight subjects of either gender were enrolled for the study. Two groups were prepared. One group was experimental group (n=36) and the second group was control group (n=36). Parameter such as age, height and weight was recorded. On the basis of variables body mass Index and body fat percentage of every subject was determined. The experiment group were put on aerobic exercises spread over duration of four weeks. Results: The mean height in group I was 163.7 cm and 165.4 cm in group II. Weight was 65.2 kg and 63.5 kgs in group II, BMI (Kg/m2) was 29.4 and 29.1, body fat was 29.3% and 29.6% in group I and II respectively. A significant difference was observed (P< 0.05). The mean pre- test BMI was 29.6 and 38.5 and post- test value was 26.4 and 38.9 in group I and II respectively. A significant difference was observed (P< 0.05). Conclusions: Regular physical activity appears to confer a health benefit to the people. There was a positive relationship between aerobic exercises and overweight women in order to reduce the value of fat in the body.

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