Cow's Milk Protein Intolerance

In Reply.— The literature has been replete with discussions of cow's milk protein hypersensitivity relevant to its diagnosis as well as clinical patterns of presentation since the entity was initially described by M. Rubin 40 years ago. Drs Gilbertson and Bentley now suggest a comparatively simple diagnostic procedure for detecting cow's milk protein intolerance (hypersensitivity) by merely inspecting the rectal mucosa of the infant at risk. My criticism of their observations relates initially to the specificity of rectal mucosal vascularity changes, as well as to the pragmatic aspects of this diagnostic procedure.