Eyelid myoclonia with absences related to epileptic negative myoclonus

2021 ◽  
Vol 23 (6) ◽  
pp. 917-921
Author(s):  
Atsuro Daida ◽  
Mina Yokoyama ◽  
Kaoru Yamamoto ◽  
Daisuke Hasegawa ◽  
Isao Kusakawa ◽  
...  
Keyword(s):  
Brain ◽  
2005 ◽  
Vol 129 (1) ◽  
pp. 65-81 ◽  
Author(s):  
Guido Rubboli ◽  
Roberto Mai ◽  
Stefano Meletti ◽  
Stefano Francione ◽  
Francesco Cardinale ◽  
...  

2010 ◽  
Vol 1 (1) ◽  
pp. 3 ◽  
Author(s):  
Vicky Chau ◽  
Sadhana Prasad ◽  
Dwight Stewart ◽  
George Heckman

Patients with Creutzfeldt–Jakob disease (CJD) may exhibit characteristic abnormalities on the electroencephalogram (EEG). However, these abnormalities have been associated with a number of cases of drug toxicity. We report a case of CJD-like syndrome associated with gabapentin. A 78-year-old man was hospitalized for recurrent falls. Three months prior to admission, gabapentin was prescribed to treat symptoms of trigeminal neuralgia. The patient subsequently presented with a two-month history of worsening gait abnormalities, negative myoclonus, and cognitive impairment. The EEG showed diffuse background slowing with larger amplitude delta discharges, which at times appeared triphasic, raising the possibility of CJD. The gait abnormalities and myoclonus resolved and the EEG normalized after the gabapentin was discontinued. Several cases of drug-induced CJD-like syndrome have been reported, mainly presenting with cognitive impairment, myoclonus, Parkinsonism, and EEG abnormalities. This patient may have been predisposed to adverse neurological effects from gabapentin owing to age, concurrent renal insufficiency, and cardiac disease. We concluded that it is imperative to include drug toxicity in the differential diagnosis of patients presenting with clinical manifestations and EEG findings suggestive of CJD, particularly in the setting of advanced age and comorbidities.


2006 ◽  
Vol 2 (4) ◽  
pp. 272 ◽  
Author(s):  
In-Uk Song ◽  
Dong-Geun Lee ◽  
Joong-Seok Kim ◽  
Jae-Young An ◽  
Sang-Bong Lee ◽  
...  

2009 ◽  
Vol 14 (4) ◽  
pp. 687-690 ◽  
Author(s):  
Hsiang-Yu Yu ◽  
Shang-Yeong Kwan ◽  
Jiing-Feng Lirng ◽  
Kwong-Kum Liao ◽  
Yum-Kung Chu ◽  
...  
Keyword(s):  

2020 ◽  
Vol 43 (1) ◽  
pp. 26-27 ◽  
Author(s):  
Özcan Uzun ◽  
Abdullah Bolu ◽  
Azize Beril Taşçi ◽  
Begüm Oğur
Keyword(s):  

1998 ◽  
Vol 29 (01) ◽  
pp. 29-34 ◽  
Author(s):  
H. Oguni ◽  
T. Uehara ◽  
T. Tanaka ◽  
M. Sunahara ◽  
M. Hara ◽  
...  

Neurology ◽  
1997 ◽  
Vol 49 (6) ◽  
pp. 1534-1537 ◽  
Author(s):  
S. Noachtar ◽  
H. Holthausen ◽  
H. O. Luders

2000 ◽  
Vol 111 (3) ◽  
pp. 471-476 ◽  
Author(s):  
Kaoru Matsunaga ◽  
Takenori Uozumi ◽  
Naoki Akamatsu ◽  
Yoshikuni Nagashio ◽  
Liu Qingrui ◽  
...  

2001 ◽  
Vol 46 (2) ◽  
pp. 99-101 ◽  
Author(s):  
Yasuyuki Okuma ◽  
Kenji Fujishima ◽  
Yutaka Machida ◽  
Naoko Inagaki ◽  
Yukihiro Sugita ◽  
...  
Keyword(s):  

2000 ◽  
Vol 31 (5) ◽  
pp. 273-275 ◽  
Author(s):  
G. Capovilla ◽  
G. Rubboli ◽  
Francesca Beccaria ◽  
Stefania Meregalli ◽  
P. Veggiotti ◽  
...  

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