La aplicación simultanea de intervenciones de control puede llevar a escenarios catastróficos para la población

Osvaldo Osuna; Jose Geiser Villavicencio Pulido

doi:10.18273/revint.v39n2-2021003

La aplicación simultanea de intervenciones de control puede llevar a escenarios catastróficos para la población

Revista Integración ◽

10.18273/revint.v39n2-2021003 ◽

2021 ◽

Vol 39 (2) ◽

Author(s):

Osvaldo Osuna ◽

Jose Geiser Villavicencio Pulido

Keyword(s):

Infectious Disease ◽

Model Solutions

We analyze the evolution of an infectious disease if infectious individuals are treated or isolated. The analysis of the model shows catastrophic scenarios for the population in which bringing R0 below 1 is not enough to decrease the number of infectious individuals. Finally, we show three scenarios for the behavior of the model solutions in which multiple endemic equilibria exist.

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Tissue section lifting for electron microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100081292 ◽

1978 ◽

Vol 36 (2) ◽

pp. 86-87

Author(s):

Adrian F. van Dellen

Keyword(s):

Infectious Disease ◽

Electron Microscopy ◽

Tissue Culture ◽

Organ System ◽

Surrounding Tissue ◽

Paraffin Sections ◽

Surface Areas ◽

Specific Determination ◽

High Degree ◽

Accuracy And Repeatability

The morphologic pathologist may require information on the ultrastructure of a non-specific lesion seen under the light microscope before he can make a specific determination. Such lesions, when caused by infectious disease agents, may be sparsely distributed in any organ system. Tissue culture systems, too, may only have widely dispersed foci suitable for ultrastructural study. In these situations, when only a few, small foci in large tissue areas are useful for electron microscopy, it is advantageous to employ a methodology which rapidly selects a single tissue focus that is expected to yield beneficial ultrastructural data from amongst the surrounding tissue. This is in essence what "LIFTING" accomplishes. We have developed LIFTING to a high degree of accuracy and repeatability utilizing the Microlift (Fig 1), and have successfully applied it to tissue culture monolayers, histologic paraffin sections, and tissue blocks with large surface areas that had been initially fixed for either light or electron microscopy.

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