scholarly journals Validation of a Novel and Sensitive RP-HPLC Method for Simultaneous Determination of Cefixime Trihydrate and Sodium Benzoate in Powder for Oral Suspension Dosage Form

2017 ◽  
Vol 2 (5) ◽  
Author(s):  
MEM Hassouna
Keyword(s):  
Simultaneous Determination ◽  
Sodium Benzoate ◽  
Dosage Form ◽  
Hplc Method ◽  
Oral Suspension ◽  
Rp Hplc

Simultaneous determination of Sulphadoxine and Pyrimethamine by taking Tolterodine as an internal standard in Pharmaceutical dosage form by RP-HPLC

2021 ◽  
pp. 145-150
Author(s):  
Sushil D. Patil ◽  
Pravin B. Shelke ◽  
Priti Aher ◽  
Maswood Ahmed Hafizur Rahman
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Internal Standard ◽  
Hplc Method ◽  
Control Analysis ◽  
Pharmaceutical Dosage Form ◽  
Quality Control Analysis ◽  
Rp Hplc ◽  
Sulphadoxine Pyrimethamine

A simple, rapid, economic, sensitive and precise HPLC method has been developed for the simultaneous determination of Sulphadoxine and Pyrimethamine in pharmaceutical dosage form by taking Tolterodine as an internal standard. The method was carried out using Phenomenex C18 (4.6ID × 250mm; 5µm) column and mobile phase comprised of methanol and Phosphate Buffer in proportion of ratio 60:40 v/v. The flow rate was 1.0mL/min and detection was carried out at 276nm. The retention time of Sulphadoxine, Pyrimethamine and Tolterodine were found to be 2.967, 4.058 and 6.908 respectively. Linearity of Sulphadoxine and Pyrimethamine in the range of 2 to 12μg/mL and 4 to 24μg/mL respectively. The % recoveries of Sulphadoxine and Pyrimethamine were found to be in between 99.93% to 99. 96 % respectively. The proposed method is suitable for the routine quality control analysis for simultaneous determination of Sulphadoxine and Pyrimethamine was in bulk and pharmaceutical dosage form.

RP-HPLC method for the simultaneous determination of Atorvastatin and Amlodipine in tablet dosage form

2006 ◽  
Vol 68 (2) ◽  
pp. 275 ◽  
Author(s):  
GG Sankar ◽  
AL Rao ◽  
JVLN Seshagirirao ◽  
KRaja Rajeswari
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Hplc Method ◽  
Rp Hplc ◽  
Tablet Dosage

SIMULTANEOUS DETERMINATION OF FINASTERIDE AND TAMSULOSIN IN COMBINED DOSAGE FORM BY USING RP-HPLC METHOD

2014 ◽  
Vol 37 (8) ◽  
pp. 1176-1186 ◽  
Author(s):  
Mahesh K. Nasare ◽  
Jetta Satish ◽  
S. Hasan Amrohi ◽  
S. Harshini ◽  
Manikanta Kumar ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Hplc Method ◽  
Rp Hplc
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