Synthetic Lethality in Breast Cancer Cells: Genes Required for Tumor Survival

2002 ◽  
Author(s):  
Gregory J. Hannon
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Synthetic Lethality ◽  
Tumor Survival

G‐Quadruplex‐Binding Small Molecule Induces Synthetic Lethality in Breast Cancer Cells by Inhibiting c‐MYC and BCL2 Expression

ChemBioChem ◽  
2020 ◽  
Vol 21 (7) ◽  
pp. 963-970 ◽  
Author(s):  
Rakesh Paul ◽  
Tania Das ◽  
Manish Debnath ◽  
Ajay Chauhan ◽  
Jyotirmayee Dash
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Small Molecule ◽  
Breast Cancer Cells ◽  
Synthetic Lethality ◽  
G Quadruplex ◽  
Bcl2 Expression

scholarly journals The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells

2017 ◽  
Vol 19 (1) ◽  
Author(s):  
Robert Hromas ◽  
Hyun-Suk Kim ◽  
Gurjit Sidhu ◽  
Elizabeth Williamson ◽  
Aruna Jaiswal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Synthetic Lethality

ATM inhibition induces synthetic lethality and enhances sensitivity of PTEN-deficient breast cancer cells to cisplatin

2018 ◽  
Vol 366 (1) ◽  
pp. 24-33 ◽  
Author(s):  
Ke Li ◽  
Huaying Yan ◽  
Wenhao Guo ◽  
Mei Tang ◽  
Xinyu Zhao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Synthetic Lethality
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