Synthesis of 4-Arylaminoquinazolines from 2-amino-N'-Arylbenzamidines and Orthoesters via the Dimroth Rearrangement of Intermediate Quinazolin-4(3H)- Imines

2019 ◽  
Vol 22 (28) ◽  
pp. 2801-2808
Author(s):  
Krzysztof Zemlak ◽  
Wojciech Szczepankiewicz ◽  
Bartłomiej Kula ◽  
Tadeusz Bieg
2017 ◽  
Vol 21 (25) ◽  
Author(s):  
Anna Krajczyk ◽  
Jerzy Boryski

1983 ◽  
Vol 48 (12) ◽  
pp. 3426-3432 ◽  
Author(s):  
Dušan Koščík ◽  
Pavol Kristian ◽  
Ondrej Forgáč

New synthesis of pyrido[3,4-e]-1,3-thiazines consisting in reaction of 2,6-dimethyl-4-chloronicotinoyl isothiocyanate with primary or secondary amines, or with benzaldehyde phenylhydrazone, is described. High reactivity of the chlorine atom does not allow isolation of the corresponding thioureas, arising as intermediates, except in the case of the benzylamino derivative. Structure of the products was unequivocally confirmed by their spectral data (IR, UV, 1H NMR, 13C NMR and mass spectra). The synthesized derivatives do not undergo the Dimroth rearrangement.


ChemInform ◽  
2004 ◽  
Vol 35 (37) ◽  
Author(s):  
Vladimir Yu. Rozhkov ◽  
Lyudmila V. Batog ◽  
Elena K. Shevtsova ◽  
Marina I. Struchkova

ChemInform ◽  
2008 ◽  
Vol 39 (50) ◽  
Author(s):  
Antonino Lauria ◽  
Ilenia Abbate ◽  
Chiara Patella ◽  
Noemi Gambino ◽  
Arturo Silvestri ◽  
...  

2006 ◽  
Vol 42 (1) ◽  
pp. 121-122 ◽  
Author(s):  
I. V. Geide ◽  
T. V. Glukhareva ◽  
A. I. Matern ◽  
Yu. Yu. Morzherin

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