False-positive and false-negative cases of fine-needle aspiration cytology for palpable breast lesions

Breast Cancer ◽  
2007 ◽  
Vol 14 (4) ◽  
pp. 388-392 ◽  
Author(s):  
Takashi Ishikawa ◽  
Yohei Hamaguchi ◽  
Mikiko Tanabe ◽  
Nobuyoshi Momiyama ◽  
Takashi Chishima ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
False Positive ◽  
Fine Needle Aspiration Cytology ◽  
False Negative ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

The diagnostic utility of cell block in fine needle aspiration cytology of palpable breast lesions in a Nigerian tertiary health institution

2020 ◽  
Vol 48 (12) ◽  
pp. 1300-1306
Author(s):  
Fred John Nnaemeka Obiajulu ◽  
Adetola Olubunmi Daramola ◽  
Charles Chidozie Anunobi ◽  
Nzechukwu Zimudo Ikeri ◽  
Fatimah Biade Abdulkareem ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Diagnostic Utility ◽  
Cell Block ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

scholarly journals Fine needle aspiration cytology (FNAC) in pre-operative diagnosis of breast lesions in Kadapa region of Andhra Pradesh, India

2017 ◽  
Vol 4 (12) ◽  
pp. 4062
Author(s):  
Chakarala Obula Reddy ◽  
Garisa Chandra Mohana Reddy
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Background: Various diagnostic methods have been developed to evaluate the palpable and non-palpable breast lesions, but Fine needle aspiration cytology of the palpable breast masses have become increasingly popular as a diagnostic technique to assess the breast lesions. To study the role of FNAC in diagnosis of breast lumps.Methods: 60 female patients (11-74 years age group) with palpable breast lump were utilized to study the role of Fine needle aspiration cytology for clinically palpable breast lump was carried out in Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh.Results: Fine needle aspiration cytology revealed benign in 22 patients, suspicious in 3 and 35 malignant lesions were 93.10% with false negative rate of 6.9% and false positive rate of 0%. The overall sensitivity of fine needle aspiration cytology in diagnosing the palpable breast lump in our study was 93.10%, specificity was 100%, positive predictive of 100% and negative predictive value of 90.47%.Conclusions: FNAC is easy to perform and painless procedure and standard tool for diagnosis of breast lumps with high percentage of true positives without virtual complications.

scholarly journals Frequency of Fine Needle Aspiration Cytological Category C5 in Breast Lesions among Females of Various Age Groups

2021 ◽  
Vol 15 (6) ◽  
pp. 1481-1483
Author(s):  
S. Yaseen ◽  
M. Ali ◽  
F. Mahmood ◽  
S. Mudassar ◽  
U. Nisar
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Age Groups ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Age Group ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Background: Benign as well as malignant neoplasm of breast still appears to be the prime tumour among females and the prevalence of the disease is increasing all over the countries. The likelihood of emergence of breast neoplasm is linked to a number of factors i.e. reproductive life events and the factor of lifestyle that modify levels of endogenous sex hormones. One of most important risk factors is growing old age. Fine needle aspiration cytology (FNAC) is a least traumatic, reliable simple, complication free technique and economical for the diagnosis of mass lesions. It can be easily repeated if an adequate aspirate is not obtained. Aim: To determine the frequency of cytological category of FNAC C5 of breast lesion among different age groups. Study Design: Cross sectional comparative research study Place and Duration of Study: Department of Histopathology, Shaikh Zayed Hospital, Lahore from 21st January 2016 to 22nd September 2016. Methodology: One hundred and twenty female patients selected who presented with complain of palpable lesion in breast and was correlated with physical examination recording the size and consistency of mass. The procedure was performed on patients with complete clinical and radiological work up. After preparation of direct smear, slides were processed according to routine processing and then stained with H&E and Giemsa. Results: Thirty (25.80%) were between 18-30 age group while 42(35.00%), 47(39.20%) were between 31-45 and 46-60 age groups respectively. Though majority of FNAC cases were found in age group 31–45 but there was no significant difference among three groups by age. Conclusion: Malignancy in palpable breast masses can surely be diagnosed by a combination of clinical examination of breast and FNAC which when performed by a dedicated cytopathologist should be an integral part of a breast screening service. Middle age group had highest frequency but difference was insignificant. Keywords: Fine needle aspiration cytology, Palpable breast lesions, Age groups

scholarly journals Cytomorphological patterns of palpable breast lesions diagnosed on fine needle aspiration cytology in females

2020 ◽  
Vol 18 ◽  
pp. 205873922094614
Author(s):  
Aamir Sharif ◽  
Tahira Tabassum ◽  
Muhammad Riaz ◽  
Muhammad Akram ◽  
Naveed Munir
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Mass ◽  
Breast Lesions ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Breast cancer is the most common malignant tumor and is a leading cause of death worldwide. This study was planned to find out the frequencies of various types of lesions from palpable breasts of female patients through fine needle aspiration cytology. This retrospective study was carried out during December 2017 to May 2018 on 100 female patients presenting with palpable breast mass at University Medical Complex & Research Center, Sargodha, Pakistan. Following written informed consent from patients, a detailed history, patient age, and clinical examination were recorded. The fine needle aspiration cytology was performed and aspirates were processed following the standard methods for cytopathological examination. The cases were grouped according to the five tier reporting format for breast lesion (C1–C5) laid down by the International Academy of Cytologists (IAC) in 2016. The spectrum of breast lesions on cytomorphological interpretation was 54% benign (C2), 2% atypia/suspicious probably benign (C3), 3% suspicious probably malignant (C4) and 41% malignant (C5). Inadequate/insufficient material (C1) was not included in the study. In this study, the specificity, sensitivity, negative and positive predictive value, and diagnostic accuracy of fine needle aspiration cytology were 100%, 91.11%, 98.18%, 100%, and 98.96%, respectively. In benign lesions, maximum cases were of fibroadenoma (24%) followed by fibrocystic disease (4%), lipoma (3%) while benign phyllodes tumor and galactocele were only 1% each. Breast mass was the chief presenting complaint. Breast cancer was commonest among all the morphological patterns of breast lesions followed by fibroadenoma. This study supports that cytological examination using fine needle aspiration cytology is an economical, rapid, easy and valuable diagnostic tool.

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