A Case of Vitiligo Vulgaris Dramatically Improved by Topical Therapy with Tacrolimus Ointment

2003 ◽  
Vol 65 (4) ◽  
pp. 331-332
Author(s):  
Hiroshi HAMADA ◽  
Takurou KANEKURA ◽  
Tamotsu KANZAKI
Keyword(s):  
Topical Therapy ◽  
Tacrolimus Ointment

scholarly journals Impact of topical anti-inflammatory therapy on morpho-functional characteristics of epidermal barrier. Optimization of atopic dermatitis treatment schedules

2018 ◽  
Vol 94 (4) ◽  
pp. 73-82 ◽  
Author(s):  
L. S. Kruglova ◽  
D. D. Petrunin
Keyword(s):  
Atopic Dermatitis ◽  
Deleterious Effect ◽  
Negative Impact ◽  
Topical Therapy ◽  
Functional Characteristics ◽  
Epidermal Structure ◽  
Epidermal Barrier ◽  
Tacrolimus Ointment ◽  
Positive Effect ◽  
Lamellae Structure

In this literature review data regarding impact of topical therapy with topical corticosteroids (TCS) and tacrolimus ointment on morpho-functional characteristics of epidermal barrier is analyzed. Whereas TCS has profound negative impact on nearly all epidermal barrier parameters, including epidermal structure and thickness, integrity and cohesion of stratum corneum, protease activity, hydration, pH, differentiation, lipid lamellae structure etc., tacrolimus ointment (Protopic®) exerts positive effect on the majority of the aforementioned parameters, thus allowing to compensate deleterious effect of TCS. These data allow defining recommendations upon optimization of topical therapy of atopic dermatitis with stepwise switching from TCS to Protopic® ointment.

Topical Therapy of Alopecia with Squaric Acid Dibutylester.

1994 ◽  
Vol 56 (1) ◽  
pp. 105-108 ◽  
Author(s):  
Hiroshi HACHISUKA ◽  
Osamu MORI ◽  
Tomoyuki MAEDA ◽  
Yoichiro SASAI
Keyword(s):  
Topical Therapy ◽  
Squaric Acid

Topical Therapy for Severe Alopecia Areata (Totalis and Universalis) with Squaric Acid Dibutylester (SADBE).

1997 ◽  
Vol 59 (2) ◽  
pp. 222-226 ◽  
Author(s):  
Naruhisa NISHIYAMA ◽  
Hideki NODA ◽  
Kenro TSUBOI
Keyword(s):  
Alopecia Areata ◽  
Topical Therapy ◽  
Squaric Acid
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