scholarly journals Cluster of atypical adult Guillain-Barré syndrome temporally associated with neurological illness due to EV-D68 in children, South Wales, United Kingdom, October 2015 to January 2016

2016 ◽  
Vol 21 (4) ◽  
Author(s):  
Christopher J Williams ◽  
Rhys H Thomas ◽  
Trevor P Pickersgill ◽  
Marion Lyons ◽  
Gwen Lowe ◽  
...  

We report a cluster of atypical Guillain–Barré syndrome in 10 adults temporally related to a cluster of four children with acute flaccid paralysis, over a 3-month period in South Wales, United Kingdom. All adult cases were male, aged between 24 and 77 years. Seven had prominent facial diplegia at onset. Available electrophysiological studies showed axonal involvement in five adults. Seven reported various forms of respiratory disease before onset of neurological symptoms. The ages of children ranged from one to 13 years, three of the four were two years old or younger. Enterovirus testing is available for three children; two had evidence of enterovirus D68 infection in stool or respiratory samples. We describe the clinical features, epidemiology and state of current investigations for these unusual clusters of illness.

2021 ◽  
Vol 9 (7) ◽  
Author(s):  
Sundus Sardar ◽  
Sreethish Sasi ◽  
Suresh Menik Arachchige ◽  
Muhammad Zahid ◽  
Gayane Melikyan

Author(s):  
Jason E. Hale ◽  
Sumayya J. Almarzouqi ◽  
Andrew G. Lee ◽  
Michael L. Morgan

2017 ◽  
Vol 5 (2) ◽  
pp. 129-131
Author(s):  
Uzzwal Kumar Mallick ◽  
Badrul Alam ◽  
Mohammad Asaduzzaman

Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy. In typical cases, the first symptoms of GBS are pain, numbness, paresthesia, weakness in the limbs. Autonomic involvement is common and causes urinary retention and ileus. Most of these symptoms overlap with those of cervical myelopathy. Therefore, correct diagnosis of GBS in a patient with symptomatic cervical myelopathy or in a patient with atypical manifestations of GBS can be difficult, especially early in the course of GBS. We report a 60-year-old man who was admitted to the neurosurgery department with worsening neck pain, numbness and weakness in the hands initially thought to be secondary to progressive cervical myelopathy. However, his symptoms rapidly progressed to flaccid areflexic quadriparesis and respiratory difficulty within few days and shifted to ICU for ventilator support. Electrophysiological studies and cerebrospinal fluid analysis were consistent with an acquired demyelinating polyradiculoneuropathy. We planned for immunotherapy with intravenous immunoglobulin , but his condition was improving day by day with conservative treatment , so immunotherapy with intravenous immunoglobulin was not initiated. Any patient presenting as unexplain Cervical myelopathy, GBS should be kept in mind before planning any surgical intervention.Bangladesh Crit Care J September 2017; 5(2): 129-131


2015 ◽  
Vol 20 (1) ◽  
pp. 32-36 ◽  
Author(s):  
J. K. Kim ◽  
S. Y. Oh ◽  
E. H. Sohn ◽  
Y. H. Hong ◽  
S. M. Jun ◽  
...  

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