Gastro-Oesophageal Reflux during 3 Months of Therapy with Ranitidine in Reflux Oesophagitis

1996 ◽  
Vol 31 (10) ◽  
pp. 954-958 ◽  
Author(s):  
J. G. Hatlebakk ◽  
A. Berstad
1990 ◽  
Vol 29 (05) ◽  
pp. 204-209
Author(s):  
B. Ugarković ◽  
D. Ivančević ◽  
D. Babić ◽  
Ž. Babić

A method is presented which combines gastro-oesophageal reflux quantification and oesophageal transit measurement so as to differentiate true reflux from residual oesophageal activity. A group of 33 subjects with gastro-oesophageal reflux symptoms and endoscopically confirmed reflux oesophagitis and a group of 21 asymptomatic subjects with normal oesophageal, gastric and duodenal endoscopic findings were examined. The subjects were given 37 MBq 99mTc-Sn-colloid in saline orally and then scintiscanned dynamically. The gastro-oesophageal quantification was done after transit measurement and after the oesophageal time activity (to detect residual oesophageal activity) reached its minimum. The difference in the reflux indices between the two groups was highly significant. In low-grade oesophagitis measured reflux was lower than in higher grades of disease. Only 4.7% false-positive results were observed with a specificity of 95%, indicating that this method may be superior to methods published earlier.


1996 ◽  
Vol 8 (2) ◽  
pp. 131-141 ◽  
Author(s):  
R. PENAGINI ◽  
M. N. SCHOEMAN ◽  
J. DENT ◽  
M. D. TIPPETT ◽  
R. H. Holloway

1984 ◽  
Vol 98 (12) ◽  
pp. 1237-1240 ◽  
Author(s):  
V. Kambič ◽  
Zora Radšel

AbstractThe authors have treated 44 patients with posterior chronic acid laryngitis. Biopsy was performed in all patients. Characteristic changes typical of the hyperregenerative or atrophic phase of reflux oesophagitis were identified in all specimens. Gastric hypersecretion was proven in all but two patients. The aetio-logic factors of acid posterior laryngitis are gastro-oesophageal reflux, with friction of both vocal processes during phonation and vocal abuse. The preferred therapy is removal of circumscribed lesions with a suitable medical regimen.


1999 ◽  
Vol 14 (7) ◽  
pp. 715-722 ◽  
Author(s):  
Hiroshi Nakase ◽  
Toshinao Itani ◽  
Jun Mimura ◽  
Toshihiko Kawasaki ◽  
Hideshi Komori ◽  
...  

1986 ◽  
Vol 79 (10) ◽  
pp. 584-587 ◽  
Author(s):  
A L Ogilvie ◽  
Michael Atkinson

Dimethicone is a common additive to antacids, although its value in the treatment of reflux oesophagitis is unproven. Its efficacy was assessed by comparing the effect of a dimethicone-containing antacid gel (Asilone Gel) with a simple antacid gel in a double-blind trial in 45 patients with reflux oesophagitis. Thirty-eight patients completed the eight-week course of therapy. Antacid therapy alone resulted in a significant improvement of both symptoms and oesophagitis in gastro-oesophageal reflux. The inclusion of dimethicone in the antacid gel preparation did not confer any benefit in terms of symptomatic assessment but did confer a small advantage with regard to objective markers of oesophageal inflammation, suggesting that a dimethicone-containing antacid is of value in the treatment of symptomatic gastro-oesophageal reflux.


Sign in / Sign up

Export Citation Format

Share Document