The Effect of Systemic Tamsulosin Hydrochloride on Choroidal Thickness Measured by Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

The choroid plays an essential role in the pathogenesis of various posterior segment diseases. However, traditional imaging methods still have limited cross-sectional observation of choroid. Enhanced depth imaging in spectral-domain optical coherence tomography (EDI SD-OCT) uses a closer scanning position to the eye to create an inverted SD-OCT image with the advantage of better depth sensitivity, which can observe choroidal structure and measure choroidal thickness (CT) accurately. At present, more and more choroidal thickness measurements have been made in normal and pathologic states, in order to understand the pathogenesis and differential diagnosis and prognosis of various diseases, especially for macular lesions. This paper would review relevant original literatures published from January 1, 2008, to February 1, 2020, to evaluate the relationship between the changes of CT with EDI SD-OCT and macular diseases.

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The Effect of Systemic Tamsulosin Hydrochloride on Choroidal Thickness Measured by Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

Current Eye Research ◽

10.3109/02713683.2015.1069854 ◽

2015 ◽

Vol 41 (7) ◽

pp. 999-999

Author(s):

Umit Yolcu ◽

Abdullah Ilhan ◽

Salih Uzun

Keyword(s):

Optical Coherence Tomography ◽

Choroidal Thickness ◽

Spectral Domain ◽

Enhanced Depth Imaging ◽

Optical Coherence ◽

Depth Imaging

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Management of Patients with Graves’ Disease and Orbital Involvement: Role of Spectral Domain Optical Coherence Tomography

Journal of Immunology Research ◽

10.1155/2018/1454616 ◽

2018 ◽

Vol 2018 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Alice Bruscolini ◽

Maurizio La Cava ◽

Magda Gharbiya ◽

Marta Sacchetti ◽

Lucia Restivo ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Choroidal Thickness ◽

Spectral Domain ◽

Enhanced Depth Imaging ◽

Clinical Activity ◽

Graves Disease ◽

Optical Coherence ◽

Depth Imaging ◽

Orbital Involvement

Purpose. To investigate the role of choroidal thickness evaluation with spectral domain optical coherence tomography (SDOCT) and enhanced depth imaging (EDI) technique in the management of patients with Graves’ disease and orbitopathy (GO). Methods. Thirty-six eyes of 18 patients with GO and 36 eyes of 18 age-matched control subjects were included in this retrospective observational study. All the subjects underwent a complete ophthalmological evaluation, including clinical activity score (CAS) and exophthalmometry. The SDOCT images of the choroid were obtained by EDI modality. Results. Choroidal thickness was significantly increased in GO than in control eyes (p<0.01). A significant correlation was found between choroidal thickness and CAS, proptosis, and the duration of disease (p<0.05). Conclusion. This study shows that choroidal thickness, evaluated with EDI-OCT, is significantly increased in patients with GO and correlates with the activity of the disease, proptosis, and duration of the disease. The choroidal thickening may reflect the ocular hemodynamic changes, and enhanced depth imaging optical coherence tomography may be a useful tool for the evaluation of orbital congestion and management of patients with Graves’ disease and orbital involvement.

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