scholarly journals Rare Case of Adult Langerhans Cell Histiocytosis: A Case Report

2019 ◽  
Vol 13 (1) ◽  
pp. 17
Author(s):  
Dinny Gustina Prihadi ◽  
Agung Firmansyah Sumantri ◽  
Hasyarati Agustina ◽  
Indra Wijaya

Background: Langerhans Cell Histiocytosis (LCH) is a disease characterized by proliferation and infiltration of histiocytes in various organs that is caused by local or systemic effects. LCH could affect bones, lungs, central nervous system, liver, thymus, skin, and lymph nodes. The diagnosis of LCH is difficult to enforce and rarely found in adults, namely 1-2 cases per million per year.Case Presentation: In Indonesia, there were very few cases of LCH in adults, one of which was found in women aged 56 years. LCH does not yet have standard treatments. The treatment is given based on location and severity, including intralesional corticosteroid injection, radiotherapy, surgical or excision curettage, and chemotherapy. Prednisone and vinblastine chemotherapy was one of chemotherapy that is given to LCH patients. Prognosis of LCH consists of various factors, one of which is the number of organs involved. This is a case report of LCH in an adult male patient with skin involvement who received chemotherapy for 6 weeks and experienced improvement.Conclusions: LCH is not only a disease of children; it is also reported in an adult. The prognosis is related to the number of organ involved and involvement of the risk organ. LCH can recur easily and accompany malignant tumors, so follow-up and long-term observations are still needed to be done.

2015 ◽  
Vol 17 (12) ◽  
Author(s):  
Hamidreza Haghighatkhah ◽  
Yousef Jafroodi ◽  
Morteza Sanei Taheri ◽  
Ramin Pourghorban ◽  
Afarin Sadeghian Dehkordy

2016 ◽  
Vol 6 (1) ◽  
pp. 45-51
Author(s):  
Deepa Das Achath ◽  
Abhishek Sanjay Ghule ◽  
Preeti Kanchan-Talreja ◽  
Sunanda Bhatnagar

ABSTRACT Fibroosseous lesions of the jaws, including juvenile ossifying fibroma (JOF), pose diagnostic and therapeutic difficulties due to their clinical, radiological, and histological variability. There are two histological varieties of it, one as psammomatoid type and second as trebacular type; here, we present a trebacular type, which is a rare variety. After the clinical examination, radiological and histological analysis, it was diagnosed as juvenile trebacular ossifying fibroma. Although JOF is an uncommon clinical entity, its aggressive local behavior and high recurrence rate means that it is important to make an early diagnosis, apply the appropriate treatment, and, especially, follow-up the patient over the long term. How to cite this article Ghule AS, Achath DD, Kanchan- Talreja P, Bhatnagar S. Juvenile Aggressive Trabecular Ossifying Fibroma of Mandible: A Rare Case Report. J Contemp Dent 2016;6(1):45-51.


2001 ◽  
Vol 36 (4) ◽  
pp. 459-468 ◽  
Author(s):  
Cecilia Bernstrand ◽  
Kerstin Cederlund ◽  
Bengt Sandstedt ◽  
Lars Åhström ◽  
Marie Lundell ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
E. Roos ◽  
M. Maas ◽  
S. J. M. Breugem ◽  
G. R. Schaap ◽  
J. A. M. Bramer

Nonbacterial osteitis is a rare autoinflammatory disease. Often it is mistaken for a tumor or osteomyelitis. We present a case of a twelve-year-old girl referred to our hospital because of a lesion of the right clavicle. The differential diagnoses were sarcoma, osteitis, and Langerhans cell histiocytosis. After biopsy the diagnosis nonbacterial osteitis (NBO) was established. Treatment of choice is a nonsteroidal anti-inflammatory drug. This case report gives a complete follow-up of the disease, showing the pitfalls of the diagnosis.


2014 ◽  
Vol 80 (4) ◽  
pp. 366-367 ◽  
Author(s):  
Emeline das Neves de Araújo Lima ◽  
Eliakim Medeiros Alves de Araújo ◽  
Patrícia Teixeira de Oliveira ◽  
Ana Miryam Costa de Medeiros

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