scholarly journals Nonbacterial Osteitis of the Clavicle: Longitudinal Imaging Series from Initial Diagnosis to Clinical Improvement

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
E. Roos ◽  
M. Maas ◽  
S. J. M. Breugem ◽  
G. R. Schaap ◽  
J. A. M. Bramer
Keyword(s):  
Case Report ◽  
Clinical Improvement ◽  
Langerhans Cell Histiocytosis ◽  
Autoinflammatory Disease ◽  
Langerhans Cell ◽  
Differential Diagnoses ◽  
Longitudinal Imaging ◽  
The Right ◽  
Established Treatment

Nonbacterial osteitis is a rare autoinflammatory disease. Often it is mistaken for a tumor or osteomyelitis. We present a case of a twelve-year-old girl referred to our hospital because of a lesion of the right clavicle. The differential diagnoses were sarcoma, osteitis, and Langerhans cell histiocytosis. After biopsy the diagnosis nonbacterial osteitis (NBO) was established. Treatment of choice is a nonsteroidal anti-inflammatory drug. This case report gives a complete follow-up of the disease, showing the pitfalls of the diagnosis.

scholarly journals Oral Langerhans cell histiocytosis: case report with follow-up of ten years

2014 ◽  
Vol 80 (4) ◽  
pp. 366-367 ◽  
Author(s):  
Emeline das Neves de Araújo Lima ◽  
Eliakim Medeiros Alves de Araújo ◽  
Patrícia Teixeira de Oliveira ◽  
Ana Miryam Costa de Medeiros
Keyword(s):  
Case Report ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell

scholarly journals Rare Case of Adult Langerhans Cell Histiocytosis: A Case Report

2019 ◽  
Vol 13 (1) ◽  
pp. 17
Author(s):  
Dinny Gustina Prihadi ◽  
Agung Firmansyah Sumantri ◽  
Hasyarati Agustina ◽  
Indra Wijaya
Keyword(s):  
Case Report ◽  
Langerhans Cell Histiocytosis ◽  
Rare Case ◽  
Malignant Tumors ◽  
Corticosteroid Injection ◽  
Langerhans Cell ◽  
Intralesional Corticosteroid ◽  
Adult Male Patient

Background: Langerhans Cell Histiocytosis (LCH) is a disease characterized by proliferation and infiltration of histiocytes in various organs that is caused by local or systemic effects. LCH could affect bones, lungs, central nervous system, liver, thymus, skin, and lymph nodes. The diagnosis of LCH is difficult to enforce and rarely found in adults, namely 1-2 cases per million per year.Case Presentation: In Indonesia, there were very few cases of LCH in adults, one of which was found in women aged 56 years. LCH does not yet have standard treatments. The treatment is given based on location and severity, including intralesional corticosteroid injection, radiotherapy, surgical or excision curettage, and chemotherapy. Prednisone and vinblastine chemotherapy was one of chemotherapy that is given to LCH patients. Prognosis of LCH consists of various factors, one of which is the number of organs involved. This is a case report of LCH in an adult male patient with skin involvement who received chemotherapy for 6 weeks and experienced improvement.Conclusions: LCH is not only a disease of children; it is also reported in an adult. The prognosis is related to the number of organ involved and involvement of the risk organ. LCH can recur easily and accompany malignant tumors, so follow-up and long-term observations are still needed to be done.

scholarly journals A Middle-Aged Female with Multiple Brownish Plaques and Nodules: A Case Report of Multiple Cutaneous Reticulohistiocytomas

2018 ◽  
Vol 16 (1) ◽  
pp. 63-65
Author(s):  
Karuna Singh Sijapati ◽  
Sudha Karki ◽  
Smriti Karki
Keyword(s):  
Case Report ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Differential Diagnoses ◽  
Middle Aged ◽  
Multicentric Reticulohistiocytosis

Non-Langerhans-Cell histiocytosis spectrum of disorders includes multicentric reticulohistiocytosis (MR) and multiple cutaneous reticulohistiocytomas (MCR), which are very uncommon granulomatous conditions. In reticulohistiocytoma, the most common sites of involvement are extensor surfaces, particularly the hands and forearms and the classical lesions are characterised by firm brown or yellow papules, nodules and plaques. As MCR is a very rare granulomatous condition, we report here a middle-aged female a case of MCR and we highlight the significance of considering reticulohistiocytoma in the differential diagnoses of chronic and persistent brownish plaques or nodules on skin. 

scholarly journals Multifocal Skeletal Tuberculosis Mimicking Langerhans Cell Histiocytosis in a Child: a Case Report With a Long-Term Follow-Up

2015 ◽  
Vol 17 (12) ◽  
Author(s):  
Hamidreza Haghighatkhah ◽  
Yousef Jafroodi ◽  
Morteza Sanei Taheri ◽  
Ramin Pourghorban ◽  
Afarin Sadeghian Dehkordy
Keyword(s):  
Case Report ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Skeletal Tuberculosis ◽  
Long Term Follow Up

scholarly journals Langerhans cell histiocytosis of the orbit and frontal sinus of the adult woman: A first case report in Poland

2019 ◽  
Vol 10 ◽  
pp. 234
Author(s):  
Kacper Kostyra ◽  
Bogusław Kostkiewicz
Keyword(s):  
Case Report ◽  
Frontal Sinus ◽  
Langerhans Cell Histiocytosis ◽  
Histopathological Examination ◽  
Langerhans Cell ◽  
Radical Excision ◽  
Multisystem Disease ◽  
Upper Eyelid ◽  
First Case ◽  
The Right

Background: Langerhans cell histiocytosis (LCH) is a term describing a clonal proliferation of pathologic Langerhans cells (histiocytes), which may manifest as unisystem (unifocal or multifocal) or multisystem disease. LCH is a rare cause of the orbital tumor with the predilection to its lateral wall which is particularly common in children. Case Description: We report an unusual case of a 33-year-old woman, 6 months after childbirth, who presented with the edema of the right orbit and upper eyelid with headaches. On physical examination, the patient had a right superior and lateral swelling of the eyelid and the orbit and right enophthalmos, without blurred vision. Magnetic resonance imaging showed well-defined, expansile, intensely homogeneously enhancing mass lesion in the right superolateral orbital rim with the destruction of the upper wall of the orbit, growing into the frontal sinus and frontal part of the cranium with the bold of the dura mater in this region. Radical excision of the tumor was achieved through a right fronto-temporo-orbito-zygomatic craniotomy. Histopathological examination had confirmed the diagnosis of the LCH. The patient was discharged home with a modified Rankin Scale score of 0. Conclusion: The main purpose of this case report is that LCH should be considered as one of the possible causes of quickly appearing tumor of the orbit in adults.

scholarly journals Langerhans Cell Histiocytosis of the Clavicle in an Adult: A Case Report and Review of the Literature

2015 ◽  
Vol 8 (3) ◽  
pp. 426-431 ◽  
Author(s):  
Toru Udaka ◽  
Michiro Susa ◽  
Kazutaka Kikuta ◽  
Kazumasa Nishimoto ◽  
Keisuke Horiuchi ◽  
...  
Keyword(s):  
Case Report ◽  
Local Recurrence ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Review Of The Literature

Langerhans cell histiocytosis (LCH) usually occurs in children under the age of 10 years with a predilection for the skull, spine, rib and humerus. Solitary LCH occurring in an adult clavicle is uncommon with limited reports to date. The lesion in our patient was curetted with the intent to make a diagnosis, which subsequently lead to the remission of the symptom and the disease. At the final follow-up after 1 year, no local recurrence or metastasis is observed.

scholarly journals Langerhans Cell Histiocytosis of the Rib in an Adult: A Case Report

2016 ◽  
Vol 9 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Sung Hyun Kim ◽  
Moon Young Choi
Keyword(s):  
Back Pain ◽  
Case Report ◽  
Local Recurrence ◽  
Bone Tumor ◽  
Langerhans Cell Histiocytosis ◽  
Osteolytic Lesion ◽  
Langerhans Cell ◽  
Pathologic Finding ◽  
Single System

Single-site, single-system Langerhans cell histiocytosis (LCH) of the rib is one of the rarest causes of bone tumor in adults. Herein, we report a case of a healthy 35-year-old male who presented with upper back pain that was attributed to a solitary osteolytic lesion at the posterolateral aspect of his sixth rib. For diagnostic confirmation and treatment, partial resection of the sixth rib was performed and pathologic finding was consistent with LCH. At the final follow-up after 2 years, no local recurrence or metastasis was observed.

scholarly journals Multisystem Langerhans cell histiocytosis coexisting with metastasizing adenocarcinoma of the lung: A case report

2013 ◽  
Vol 70 (12) ◽  
pp. 1159-1161
Author(s):  
Aleksandra Lovrenski ◽  
Mirna Djuric ◽  
Istvan Klem ◽  
Zivka Eri ◽  
Milana Panjkovic ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Adenocarcinoma ◽  
Langerhans Cells ◽  
Langerhans Cell Histiocytosis ◽  
Incidental Finding ◽  
Lung Parenchyma ◽  
Langerhans Cell ◽  
Heavy Smoker ◽  
Unknown Etiology ◽  
The Right

Introduction. Langerhans cell histiocytosis (LCH) is an uncommon disease of unknown etiology characterized by uncontrolled proliferation and infiltration of various organs by Langerhans cells. Case report. We presented a 54-year-old man, heavy smoker, with dyspnea, cough, hemoptysis, headache and ataxia, who died shortly after admission to our hospital. On the autopsy, tumor was found in the posterior segment of the right upper pulmonary lobe as well as a right-sided occipitoparietal lesion which penetrated into the right ventricle resulting in internal and external hematocephalus. Histologically and immunohistohemically, the diagnosis of primary lung adenocarcinoma with brain metastasis was made (tumor cells showed positivity for CK7 and TTF-1 which confirmed the diagnosis). In the lung parenchyma around the tumor, as well as in brain tissue around the metastatic adenocarcinoma histiocytic lesions were found. Light microscopic examination of the other organs also showed histiocytic lesions involving the pituitary gland, hypothalamus, spleen and mediastinal lymph nodes. Immunohistochemical studies revealed CD68, S-100 and CD1a immunoreactivity within the histiocytes upon which the diagnosis of Langerhans' cells histiocytosis was made. Conclusion. The multisystem form of LCH with extensive organ involvement was an incidental finding, while metastatic lung adenocarcinoma to the brain that led to hematocephalus was the cause of death.

scholarly journals Long-standing necrobiotic xanthogranuloma limited to the skin: A case report

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110579
Author(s):  
Anne-Sophie Smilga ◽  
Mona Lavoie ◽  
Sungmi Jung ◽  
Ariane Schreiber
Keyword(s):  
Case Report ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Monoclonal Gammopathies ◽  
Malignant Condition

Necrobiotic xanthogranuloma is a rare non-Langerhans cell histiocytosis with a known association with monoclonal gammopathies and malignant conditions. There is a lack of consensus regarding the management of necrobiotic xanthogranuloma. In this case report, the patient is diagnosed with a long-standing necrobiotic xanthogranuloma limited to the skin. Although all initial investigations were reassuring, the patient remains at a higher risk of developing a malignant condition. The goal of the authors is to highlight the need for clearer investigation and follow-up guidelines.

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