Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics

Potential Drug ◽

Modeling Approach ◽

Optimal Dosing ◽

Physiologically Based ◽

Dosing Regimens

Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Cited By ~ 1

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Modeling Approach ◽

A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1992 ◽

2016 ◽

Vol 37 (1) ◽

pp. 15-27 ◽

Cited By ~ 8

Author(s):

Ian Templeton ◽

Paulien Ravenstijn ◽

Carlo Sensenhauser ◽

Jan Snoeys

Keyword(s):

Drug Interactions ◽

Modeling Approach ◽

A Physiologically-Based Pharmacokinetic Modeling Approach To Predict Drug–Drug Interactions of Sonidegib (LDE225) with Perpetrators of CYP3A in Cancer Patients

Drug Metabolism and Disposition ◽

10.1124/dmd.116.073585 ◽

2017 ◽

Vol 45 (4) ◽

pp. 361-374 ◽

Cited By ~ 4

Author(s):

Heidi J. Einolf ◽

Jocelyn Zhou ◽

Christina Won ◽

Lai Wang ◽

Sam Rebello

Keyword(s):

Drug Interactions ◽

Cancer Patients ◽

Modeling Approach ◽

A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2013.79 ◽

2013 ◽

Vol 94 (2) ◽

pp. 260-268 ◽

Cited By ~ 49

Author(s):

K K Machavaram ◽

L M Almond ◽

A Rostami-Hodjegan ◽

I Gardner ◽

M Jamei ◽

...

Keyword(s):

Drug Interactions ◽

Modeling Approach ◽

A Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug-Drug Interactions of Buprenorphine After Subcutaneous Administration of CAM2038 With Perpetrators of CYP3A4

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.10.035 ◽

2018 ◽

Vol 107 (3) ◽

pp. 942-948

Author(s):

Tao Liu ◽

Jogarao V.S. Gobburu

Keyword(s):

Drug Interactions ◽

Subcutaneous Administration ◽

Modeling Approach ◽

Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug‐Drug Interactions or in Special Populations: An Example Using Tofacitinib

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1679 ◽

2020 ◽

Vol 60 (12) ◽

pp. 1617-1628

Author(s):

Susanna Tse ◽

Martin E. Dowty ◽

Sujatha Menon ◽

Pankaj Gupta ◽

Sriram Krishnaswami

Keyword(s):

Drug Interactions ◽

Drug Exposure ◽

Special Populations ◽

Potential Drug ◽

Assessing Potential Drug-Drug Interactions Between Dabigatran Etexilate and a P-Glycoprotein Inhibitor in Renal Impairment Populations Using Physiologically Based Pharmacokinetic Modeling

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12382 ◽

2019 ◽

Vol 8 (2) ◽

pp. 118-126 ◽

Cited By ~ 5

Author(s):

Kosuke Doki ◽

Sibylle Neuhoff ◽

Amin Rostami-Hodjegan ◽

Masato Homma

Keyword(s):

Renal Impairment ◽

Drug Interactions ◽

Dabigatran Etexilate ◽

Potential Drug ◽

P Glycoprotein ◽

Physiologically based pharmacokinetic modeling to predict complex drug-drug interactions: a case study of AZD2327 and its metabolite, competitive and time-dependent CYP3A inhibitors

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1962 ◽

2015 ◽

Vol 36 (8) ◽

pp. 507-519 ◽

Cited By ~ 4

Author(s):

Jian Guo ◽

Diansong Zhou ◽

Yan Li ◽

Bui H. Khanh

Keyword(s):

Drug Interactions ◽

Time Dependent ◽

Physiologically Based ◽

Complex Drug

Pain Chemogenomics Knowledgebase (Pain-CKB) for Systems Pharmacology Target Mapping and Physiologically Based Pharmacokinetic Modeling Investigation of Opioid Drug–Drug Interactions

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.0c00372 ◽

2020 ◽

Vol 11 (20) ◽

pp. 3245-3258

Author(s):

Mingzhe Shen ◽

Maozi Chen ◽

Tianjian Liang ◽

Siyi Wang ◽

Ying Xue ◽

...

Keyword(s):

Drug Interactions ◽

Systems Pharmacology ◽

Physiologically‐Based Pharmacokinetic Modeling for Predicting Drug Interactions of a Combination of Olanzapine and Samidorphan

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12488 ◽

2020 ◽

Vol 9 (2) ◽

pp. 106-114 ◽

Cited By ~ 2

Author(s):

Lei Sun ◽

Lisa Moltke ◽

Karen Rowland Yeo

Keyword(s):

Drug Interactions ◽