Faculty Opinions recommendation of Development of orally bioavailable and CNS penetrant biphenylaminocyclopropane carboxamide bradykinin B1 receptor antagonists.

2007 ◽  
Author(s):  
Thomas W von Geldern
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor ◽  
Orally Bioavailable

Discovery of Potent, Orally Bioavailable Phthalazinone Bradykinin B1 Receptor Antagonists

2011 ◽  
Vol 54 (20) ◽  
pp. 7232-7246 ◽  
Author(s):  
Kaustav Biswas ◽  
Tanya A. N. Peterkin ◽  
Marian C. Bryan ◽  
Leyla Arik ◽  
Sonya G. Lehto ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor ◽  
Orally Bioavailable

Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists

2008 ◽  
Vol 18 (16) ◽  
pp. 4477-4481 ◽  
Author(s):  
Jian Jeffrey Chen ◽  
Wenyuan Qian ◽  
Kaustav Biswas ◽  
Vellarkad N. Viswanadhan ◽  
Benny C. Askew ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor

Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency

2012 ◽  
Vol 22 (2) ◽  
pp. 1061-1067 ◽  
Author(s):  
Wenyuan Qian ◽  
Jian Jeffrey Chen ◽  
Jason Human ◽  
Toshihiro Aya ◽  
Jiawang Zhu ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor

Indazole derivatives as novel bradykinin B1 receptor antagonists

2010 ◽  
Vol 20 (23) ◽  
pp. 7011-7014 ◽  
Author(s):  
Vera Bodmer-Narkevitch ◽  
Neville J. Anthony ◽  
Victoria Cofre ◽  
Samson M. Jolly ◽  
Kathy L. Murphy ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor

2,3-Diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B1 receptor antagonists

2005 ◽  
Vol 15 (9) ◽  
pp. 2385-2388 ◽  
Author(s):  
Dong-Mei Feng ◽  
Jenny M. Wai ◽  
Scott D. Kuduk ◽  
Christina Ng ◽  
Kathy L. Murphy ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor

From Bradykinin B2 Receptor Antagonists to Orally Active and Selective Bradykinin B1 Receptor Antagonists

2012 ◽  
Vol 55 (6) ◽  
pp. 2574-2584 ◽  
Author(s):  
Martine Barth ◽  
Michel Bondoux ◽  
Jean-Michel Luccarini ◽  
Vincent Peyrou ◽  
Pierre Dodey ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Bradykinin B2 Receptor ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor ◽  
Orally Active

Quinolinyl- and phenantridinyl-acetamides as bradykinin B1 receptor antagonists

2012 ◽  
Vol 22 (9) ◽  
pp. 3095-3099 ◽  
Author(s):  
János Éles ◽  
Gyula Beke ◽  
István Vágó ◽  
Éva Bozó ◽  
József Huszár ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor

Potent bradykinin B1 receptor antagonists: 4-Substituted phenyl cyclohexanes

2007 ◽  
Vol 17 (11) ◽  
pp. 3006-3009 ◽  
Author(s):  
Dai-Shi Su ◽  
John L. Lim ◽  
M. Kristine Markowitz ◽  
Bang-Lin Wan ◽  
Kathy L. Murphy ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor

A new class of bradykinin B1 receptor antagonists with high oral bioavailability and minimal PXR activity

2008 ◽  
Vol 18 (2) ◽  
pp. 682-687 ◽  
Author(s):  
Dong-Mei Feng ◽  
Robert M. DiPardo ◽  
Jenny M. Wai ◽  
Ronald K. Chang ◽  
Christina N. Di Marco ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
Receptor Antagonists ◽  
New Class ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor

1-Benzylbenzimidazoles: The discovery of a novel series of bradykinin B1 receptor antagonists

2008 ◽  
Vol 18 (18) ◽  
pp. 5027-5031 ◽  
Author(s):  
Qin Guo ◽  
Jayaraman Chandrasekhar ◽  
David Ihle ◽  
David J. Wustrow ◽  
Bertrand L. Chenard ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
B1 Receptor ◽  
Bradykinin B1 Receptor
Sign in / Sign up

Export Citation Format

Share Document