Faculty Opinions recommendation of A case of bronchiolitis obliterans organising pneumoniae (BOOP) after nine months post-operative irradiation for breast cancer.

2008 ◽  
Author(s):  
Gary Epler
Keyword(s):  
Breast Cancer ◽  
Bronchiolitis Obliterans

scholarly journals A case of bronchiolitis obliterans organising pneumoniae (BOOP) after nine months post-operative irradiation for breast cancer

2008 ◽  
Vol 37 (2) ◽  
pp. 235-235 ◽  
Author(s):  
Luisa Bissoli ◽  
Vincenzo Di Francesco ◽  
Filippo Valbusa ◽  
Alessandra Zivelonghi ◽  
Francesco Fantin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bronchiolitis Obliterans

scholarly journals Cryptogenic organizing pneumonia after radiotherapy for breast cancer

2010 ◽  
Vol 5 ◽  
Author(s):  
Giorgio Fumagalli ◽  
Claudio M. Sanguinetti
Keyword(s):  
Breast Cancer ◽  
Bronchiolitis Obliterans ◽  
Hormone Treatment ◽  
Organizing Pneumonia ◽  
Disease Relapse ◽  
Cryptogenic Organizing Pneumonia ◽  
Bronchiolitis Obliterans Organizing Pneumonia ◽  
Radiation Fields ◽  
Bilateral Lung ◽  
Withdrawal Of Therapy

We report a case of fever, dyspnea, respiratory failure and migratory, recurrent and bilateral lung opacities 4 months after radiotherapy and hormone therapy following surgery for breast cancer. Computerized tomography (CT) scans showed infiltrates outside the radiation fields. Bronchoalveolar lavage revealed lymphocytic alveolitis, whereas laboratory analysis demonstrated a mild systemic inflammation. Systemic steroids resulted in clinical and radiological improvement, but a disease relapse was evident at withdrawal of therapy, with definitive clinical and radiological normalization after a second cycle of therapy. This is a case of cryptogenic organizing pneumonia (COP) (previously known as bronchiolitis obliterans organizing pneumonia) primed by radiotherapy, as in previously reported cases. It is extremely important to be aware of the possibility of this complication, in order to optimize radiation and hormone treatment of breast cancer.

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