N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis
2012 ◽
Vol 8
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pp. 398-402
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The Past
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The interplay between metals and N-heterocyclic carbenes (NHCs) has provided a window of opportunities for the development of novel catalytic strategies within the past few years. The recent successful combination of Brønsted acids with NHCs has added a new dimension to the field of cooperative catalysis, enabling the stereoselective synthesis of functionalized pyrrolidin-2-ones as valuable scaffolds in heterocyclic chemistry. This Commentary will briefly highlight the concept of N-heterocyclic carbene/Brønsted acid cooperative catalysis as a new and powerful methodology in organic chemistry.
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2014 ◽
Vol 356
(16)
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pp. 3451-3455
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2019 ◽
Vol 58
(8)
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pp. 2495-2499
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