scholarly journals Measurement of liver and spleen stiffness by acoustic radiation force impulse elastography for noninvasive detection of esophageal varices in Egyptian cirrhotic patients

2019 ◽  
Vol 31 (1) ◽  
pp. 78
Author(s):  
MohamedO Khalifa ◽  
OssamaA Ahmed ◽  
YasserA Elhossary ◽  
RamyS.A Hamid
Keyword(s):  
Esophageal Varices ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Noninvasive Detection ◽  
Spleen Stiffness ◽  
Cirrhotic Patients

Measurement of Spleen Stiffness by Acoustic Radiation Force Impulse Imaging Identifies Cirrhotic Patients With Esophageal Varices

2013 ◽  
Vol 144 (1) ◽  
pp. 92-101.e2 ◽  
Author(s):  
Yoshitaka Takuma ◽  
Kazuhiro Nouso ◽  
Youichi Morimoto ◽  
Junko Tomokuni ◽  
Akiko Sahara ◽  
...  
Keyword(s):  
Esophageal Varices ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Spleen Stiffness ◽  
Cirrhotic Patients

scholarly journals A New Sampling Method for Spleen Stiffness Measurement Based on Quantitative Acoustic Radiation Force Impulse Elastography for Noninvasive Assessment of Esophageal Varices in Newly Diagnosed HCV-Related Cirrhosis

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Leonardo Rizzo ◽  
Massimo Attanasio ◽  
Marilia Rita Pinzone ◽  
Massimiliano Berretta ◽  
Michele Malaguarnera ◽  
...  
Keyword(s):  
Likelihood Ratio ◽  
Esophageal Varices ◽  
Predictive Value ◽  
Sampling Method ◽  
Acoustic Radiation ◽  
Positive Likelihood Ratio ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Cirrhotic Patients

In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with Chronic Hepatitis C (CHC) F1–F3, and 63 healthy controls. VTTQ-SS was significantly higher among cirrhotic patients with EV (3.37 m/s) in comparison with controls (2.19 m/s,P<0.001), CHC patients (2.37 m/s,P<0.001), and cirrhotic patients without EV (2.7 m/s,P<0.001). Moreover, VTTQ-SS was significantly higher among cirrhotic patients without EV in comparison with both controls (P<0.001) and CHC patients (P<0.01). The optimal VTTQ-SS cut-off value for predicting EV was 3.1 m/s (AUROC = 0.96, sensitivity 96.4%, specificity 88.5%, positive predictive value 90%, negative predictive value 96%, positive likelihood ratio 8.36, and negative likelihood ratio 0.04). In conclusion, VTTQ-SS is a promising noninvasive and reliable diagnostic tool to screen cirrhotic patients for EV and reduce the need for upper gastrointestinal endoscopy. By using our cut-off value of 3.1 m/s, we would avoid endoscopy in around 45% of cirrhotic subjects, with significant time and cost savings.

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