Reconstruction following excision of malignant scalp tumors with split thickness skin graft with and without acellular dermal matrix: A comparative study

Objective: To determine the frequency of success of acellular dermal matrix and split thickness skin graft in release of post burn contractures in hand using Vancouver scar scale. Study Design: Descriptive Case Series. Setting: Department of Plastic Surgery, Jinnah Burn and Reconstructive Surgery Center, Lahore. Period: 1st March, 2019 to 30th October, 2019. Material & Method: A descriptive case series conducted at Plastic Surgery Department, Jinnah Burn and Reconstructive Surgery Center, Lahore. A sample size of 75 patients, who full filled the inclusion criteria, was selected through non probability consecutive sampling Informed consent was obtained from all the patients. Pre-operative photography was done to compare the post-operative results. After the release of contractures, coverage with acellular dermis and split thickness skin graft was performed. All the patients were followed up to 2 months and the outcome was assessed by Vancouver Scar Scale. The collected data was entered and analyzed by using SPSS version 20. Descriptive statistics were calculated. Quantitative variables like age, size of scar were presented as mean, ± standard deviation. Qualitative variables were presented as frequencies and percentages. Results: Mean age of patient was 30 ± 9 years. Among them 40 were males and 35 females. Vancouver scale showed successful outcome (score ≤4) in 70.66 % of the patients. Partial release of contracture was the major complication seen in 5.33% of cases. Conclusion: Acelluar dermal matrix followed by split thickness skin graft is a very reliable option for coverage after release of post-burn contractures in hand as it provides very pliable, thin and lax skin with good color match and better contour to surrounding tissue.

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Prospective Randomized Comparison of Scar Appearances between Cograft of Acellular Dermal Matrix with Autologous Split-Thickness Skin and Autologous Split-Thickness Skin Graft Alone for Full-Thickness Skin Defects of the Extremities

Plastic & Reconstructive Surgery ◽

10.1097/prs.0000000000001204 ◽

2015 ◽

Vol 135 (3) ◽

pp. 609e-616e ◽

Cited By ~ 15

Author(s):

Ju Won Yi ◽

Jae Kwang Kim

Keyword(s):

Skin Graft ◽

Acellular Dermal Matrix ◽

Split Thickness Skin Graft ◽

Full Thickness ◽

Dermal Matrix ◽

Skin Defects ◽

Full Thickness Skin ◽

Thickness Skin ◽

Acellular Dermal

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The Use of the PlasmaBlade and Acellular Dermal Matrix in Rhinophyma Surgery

Journal of Cutaneous Medicine and Surgery ◽

10.1177/1203475415612422 ◽

2015 ◽

Vol 20 (2) ◽

pp. 155-158 ◽

Cited By ~ 4

Author(s):

Adem Özkan ◽

Adem Topkara ◽

Ramazan Hakan Özcan ◽

Sadık Şentürk

Keyword(s):

Skin Graft ◽

Combined Treatment ◽

Acellular Dermal Matrix ◽

Split Thickness Skin Graft ◽

Dermal Matrix ◽

Severe Acne ◽

Thickness Skin ◽

Aesthetic Results ◽

End Stage ◽

Acellular Dermal

Background: Rhinophyma is a rare, disfiguring disease characterized by a slow progressive overgrowth of the soft tissue of the nose associated with end-stage severe acne rosacea. Objective: We present a case of severe rhinophyma treated successfully using PlasmaBlade and acellular dermal matrix with split-thickness skin graft. Methods: This procedure combines deep excision with PlasmaBlade followed by coverage with an acellular dermal matrix for dermal substitution and split-thickness skin graft. Results: Functional and aesthetic results were satisfactory. Conclusion: We offer a new approach to surgical treatment of rhinophyma. Total excision of phymatous tissue and single session replacement of epidermal-dermal components is an effective treatment for patients with severe rhinophyma, resulting in satisfactory functional and aesthetic outcome. This combined treatment modality prevents the recurrence of rhinophyma. It should be considered an appropriate alternative in cases of severe rhinophyma.

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Prospective Randomized Comparison of Scar Appearances between Cograft of Acellular Dermal Matrix with Autologous Split Thickness Skin and Autologous Split Thickness with Skin Graft Alone for Full Thickness Skin Defects on the Extremity

The Journal Of Hand Surgery ◽

10.1016/j.jhsa.2016.07.024 ◽

2016 ◽

Vol 41 (9) ◽

pp. S14

Author(s):

Jae Kwang Kim

Keyword(s):

Skin Graft ◽

Acellular Dermal Matrix ◽

Full Thickness ◽

Dermal Matrix ◽

Skin Defects ◽

Full Thickness Skin ◽

Thickness Skin ◽

Acellular Dermal

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Improving Outcomes in Anterolateral Thigh Flap Donor-Site Reconstruction Using Propeller Flaps: A Retrospective Comparative Study with Skin Grafting

Journal of Reconstructive Microsurgery ◽

10.1055/s-0040-1718550 ◽

2020 ◽

Author(s):

Domenico Pagliara ◽

Maria Lucia Mangialardi ◽

Stefano Vitagliano ◽

Valentina Pino ◽

Marzia Salgarello

Keyword(s):

Comparative Study ◽

Skin Graft ◽

Donor Site ◽

Split Thickness Skin Graft ◽

Tactile Sensitivity ◽

Aesthetic Outcome ◽

Propeller Flap ◽

Thickness Skin ◽

Anterolateral Thigh ◽

Alt Flap

Abstract Background After anterolateral thigh (ALT) flap harvesting, skin graft of the donor site is commonly performed. When the defect width exceeds 8 cm or 16% of thigh circumference, it can determine lower limb function impairment and poor aesthetic outcomes. In our comparative study, we assessed the functional and aesthetic outcomes related to ALT donor-site closure with split-thickness skin graft compared with thigh propeller flap. Methods We enrolled 60 patients with ALT flap donor sites. We considered two groups of ALT donor-site reconstructions: graft group (30 patients) with split-thickness skin graft and flap group (30 patients) with local perforator-based propeller flap. We assessed for each patient the range of motion (ROM) at the hip and knee, tension, numbness, paresthesia, tactile sensitivity, and gait. Regarding the impact on daily life activities, patients completed the lower extremity functional scale (LEFS) questionnaire. Patient satisfaction for aesthetic outcome was obtained with a 5-point Likert scale (from very poor to excellent). Results In the propeller flap group, the ROMs of hip and knee and the LEFS score were significantly higher. At 12-month follow-up, in the graft group, 23 patients reported tension, 19 numbness, 16 paresthesia, 22 reduction of tactile sensitivity, and 5 alteration of gait versus only 5 patients experienced paresthesia and 7 reduction of tactile sensitivity in the propeller flap group. The satisfaction for aesthetic outcome was significantly higher in the propeller flap group. Conclusion In high-tension ALT donor-site closure, the propeller perforator flap should always be considered to avoid split-thickness skin graft with related functional and aesthetic poor results.

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Nanofiber-acellular dermal matrix as a bilayer scaffold containing mesenchymal stem cell for healing of full-thickness skin wounds

Cell and Tissue Research ◽

10.1007/s00441-018-2927-6 ◽

2018 ◽

Vol 375 (3) ◽

pp. 709-721 ◽

Cited By ~ 4

Author(s):

Mohamad Javad Mirzaei-parsa ◽

Hossein Ghanbari ◽

Behnam Alipoor ◽

Amirhossein Tavakoli ◽

Mohammad Reza H. Najafabadi ◽

...

Keyword(s):

Stem Cell ◽

Mesenchymal Stem Cell ◽

Acellular Dermal Matrix ◽

Skin Wounds ◽

Full Thickness ◽

Dermal Matrix ◽

Full Thickness Skin ◽

Thickness Skin ◽

Acellular Dermal

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Reconstruction for Defects of Total Nail Bed and Germinal Matrix Loss with Acellular Dermal Matrix Coverage and Subsequently Skin Graft

Medicina ◽

10.3390/medicina56010017 ◽

2020 ◽

Vol 56 (1) ◽

pp. 17

Author(s):

Tsung-Hsien Liu ◽

Meng-Chien Hsieh ◽

Ping-Ruey Chou ◽

Shu-Hung Huang

Keyword(s):

Skin Graft ◽

Donor Site ◽

Acellular Dermal Matrix ◽

Dermal Matrix ◽

Germinal Matrix ◽

Nail Bed ◽

Staged Operation ◽

Matrix Loss ◽

Bone Exposure ◽

Acellular Dermal

Background and Objectives: Nail bed and germinal matrix loss due to wide excision for fingertip tumors or malignancy are occasionally encountered complications. These defects also result from severely comminuted fingertip crush injuries. Large-area dorsal finger or toenail bed defects, which usually present with phalangeal bone exposure, remain challenging regardless of the usage of different reconstruction strategies. This study aimed to evaluate the clinical outcome of a staged operation with an acellular dermal matrix coverage and subsequent skin graft as reconstruction for defects of total nail bed, germinal matrix loss, and bone exposure. Materials and Methods: From April 2018 to October 2019, four patients with total nail bed, germinal matrix, and bone exposure loss after surgery were enrolled in our series. A staged operation of the acellular dermal matrix coverage with subsequent skin graft was performed on these patients. Skin graft take rate, oncological prognosis, and cosmetic outcome were evaluated. Patients were followed up for 5–13 months. An excellent skin graft take rate with a satisfying aesthetic result without local malignancy recurrence was noted. Minimal functional deficit and donor site morbidity were reported. Results: A staged operation with acellular dermal matrix coverage and subsequent skin graft proves to serve as a feasible strategy for patients who experience total nail bed, germinal matrix loss, and bone exposure after surgery. Conclusions: This reconstruction method provides a reliable repair result, satisfying aesthetic outcomes, as well as having minimal functional deficits and donor site morbidity.

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