IPX-750, A Dopamine Gluconamine That Binds D1/D5 Receptors and Has Anti-Parkinsonian Effects in Three Animal Models, is Transported across the Blood Brain Barrier

Author(s):  
Roger Laine
Physiology ◽  
1992 ◽  
Vol 7 (1) ◽  
pp. 30-34
Author(s):  
JL Williams ◽  
KL Barnes ◽  
KB Brosnihan ◽  
CM Ferrario

The area postrema, which does not have a blood-brain barrier, can sense changes in levels of blood-borne hormones. This circumventricular organ plays an important role in animal models of hypertension, recovery from hemorrhage, control of baroreflexes, and homeostasis of water and ions.


2011 ◽  
Author(s):  
Meaghan A. O’Reilly ◽  
Yuexi Huang ◽  
Kullervo Hynynen ◽  
Yoichiro Matsumoto ◽  
Lawrence A. Crum ◽  
...  

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