Tintelingen in de handen, wat nu?

Author(s):  
S. ROGGEMAN ◽  
K. DE COCK ◽  
E. JOOS

Tingling hands, what is wrong? A patient was sent to the physical medicine and rehabilitation department for advice and electromyography because of paraesthesia and functional impairment of the left hand. Such complaints are a frequent reason for seeking medical consult. Based on the most frequent causes of paraesthesia of the hand, this article aims to provide a tool to draw up a list of the most probable diagnosis and differential diagnosis through anamnesis and clinical examination.

Author(s):  
Bruce Mackay

The broadest application of transmission electron microscopy (EM) in diagnostic medicine is the identification of tumors that cannot be classified by routine light microscopy. EM is useful in the evaluation of approximately 10% of human neoplasms, but the extent of its contribution varies considerably. It may provide a specific diagnosis that can not be reached by other means, but in contrast, the information obtained from ultrastructural study of some 10% of tumors does not significantly add to that available from light microscopy. Most cases fall somewhere between these two extremes: EM may correct a light microscopic diagnosis, or serve to narrow a differential diagnosis by excluding some of the possibilities considered by light microscopy. It is particularly important to correlate the EM findings with data from light microscopy, clinical examination, and other diagnostic procedures.


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