Peer Review #1 of "Clinical impact of albumin in advanced head and neck cancer patients with free flap reconstruction—a retrospective study (v0.2)"

Abstract Background: The latency of the swallowing reflex is an important factor causing dysphagia in head and neck cancer patients. Although there are many reports comparing voluntary swallowing function before and after treatment, few studies have focused on the latency of the swallowing reflex, which is a risk factor for pneumonia due to silent aspiration. The aim of this retrospective study was to clarify the changes in the latency of the swallowing reflex before and after treatment. Methods: The latency of the swallowing reflex was quantified using the time from the injection of 1 ml of distilled water into the pharynx through a nasal catheter to the onset of swallowing. Results: The latency time of the swallowing reflex was significantly decreased 3 months after treatment compared to before treatment. A significant reduction was also observed in patients with pharyngeal cancer who underwent chemoradiation therapy. Conclusions: This retrospective study showed that a delayed swallowing reflex improved with treatment in advanced head and neck cancer patients.

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Low Skeletal Muscle Mass Predicts Discharge Disposition after Free Flap Reconstruction in Head and Neck Cancer Patients

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2019.11.161 ◽

2020 ◽

Vol 106 (5) ◽

pp. 1166-1167

Author(s):

A.J. Jones ◽

V.J. Campiti ◽

M. Alwani ◽

L.J. Novinger ◽

A. Bonetto ◽

...

Keyword(s):

Skeletal Muscle ◽

Head And Neck Cancer ◽

Head And Neck ◽

Cancer Patients ◽

Muscle Mass ◽

Neck Cancer ◽

Skeletal Muscle Mass ◽

Flap Reconstruction ◽

Free Flap Reconstruction ◽

Discharge Disposition

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60 Speech and swallowing outcomes in head and neck cancer patients with jejunal free flap reconstruction of the hypopharynx

British Journal of Oral and Maxillofacial Surgery ◽

10.1016/s0266-4356(10)60061-7 ◽

2010 ◽

Vol 48 ◽

pp. S16

Author(s):

R. Walker ◽

P. Praveen ◽

S. Parmar ◽

T. Martin ◽

R. Anand ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Cancer Patients ◽

Neck Cancer ◽

Free Flap ◽

Flap Reconstruction ◽

Free Flap Reconstruction ◽

Swallowing Outcomes

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Improvement of a Delayed Swallowing Reflex with Treatment in Advanced Head and Neck Cancer Patients

10.21203/rs.3.rs-16480/v1 ◽

2020 ◽

Author(s):

Akira Ohkoshi ◽

Kengo Kato ◽

Takenori Ogawa ◽

Ayako Nakanome ◽

Ryo Ishii ◽

...

Keyword(s):

Head And Neck Cancer ◽

Retrospective Study ◽

Head And Neck ◽

Cancer Patients ◽

Neck Cancer ◽

Advanced Head ◽

Pharyngeal Cancer ◽

Swallowing Function ◽

Before And After ◽

Swallowing Reflex

Abstract Background The latency of the swallowing reflex is an important factor causing dysphagia in head and neck cancer patients. Although there are many reports comparing swallowing function before and after treatment, few studies have focused on the latency of the swallowing reflex. The aim of this retrospective study was to clarify the changes in the latency of the swallowing reflex before and after treatment. Methods The latency of the swallowing reflex was quantified using the time from the injection of 1 ml of distilled water into the pharynx through a nasal catheter to the onset of swallowing. Results The latency time of the swallowing reflex was significantly decreased 3 months after treatment compared to before treatment. Significant reduction was also observed in patients with pharyngeal cancer who underwent chemoradiation therapy. Conclusions This retrospective study showed that a delayed swallowing reflex improved with treatment in advanced head and neck cancer patients.

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