aristolochene synthase
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scholarly journals Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase

Biochemistry ◽  
2016 ◽  
Vol 55 (20) ◽  
pp. 2864-2874 ◽  
Author(s):  
Mengbin Chen ◽  
Wayne K. W. Chou ◽  
Naeemah Al-Lami ◽  
Juan A. Faraldos ◽  
Rudolf K. Allemann ◽  
...  
Keyword(s):  
Active Site ◽  
Cyclization Reaction ◽  
Aristolochene Synthase ◽  
Site Water

scholarly journals Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate

2016 ◽  
Vol 52 (97) ◽  
pp. 14027-14030 ◽  
Author(s):  
Juan A. Faraldos ◽  
Daniel J. Grundy ◽  
Oscar Cascon ◽  
Stefano Leoni ◽  
Marc W. van der Kamp ◽  
...  
Keyword(s):  
Natural Product ◽  
Enzymatic Synthesis ◽  
Penicillium Roqueforti ◽  
Natural Substrate ◽  
Aristolochene Synthase

Aristolochene synthase from Penicillium roqueforti converts 7-methylene-FDP, a substrate the enzyme never encounters in nature, to the natural product (+)-aristolochene.

scholarly journals Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase

2015 ◽  
Vol 10 (7) ◽  
pp. 1729-1736 ◽  
Author(s):  
Kathleen A. Rising ◽  
Charisse M. Crenshaw ◽  
Hyun Jo Koo ◽  
Thangaiah Subramanian ◽  
Kareem A. H. Chehade ◽  
...  
Keyword(s):  
Farnesyl Diphosphate ◽  
Aristolochene Synthase

Conformational Change and Ligand Binding in the Aristolochene Synthase Catalytic Cycle

Biochemistry ◽  
2013 ◽  
Vol 52 (45) ◽  
pp. 8094-8105 ◽  
Author(s):  
Marc W. van der Kamp ◽  
Jitnapa Sirirak ◽  
Jolanta Żurek ◽  
Rudolf K. Allemann ◽  
Adrian J. Mulholland
Keyword(s):  
Ligand Binding ◽  
Conformational Change ◽  
Catalytic Cycle ◽  
Aristolochene Synthase

scholarly journals Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase

Biochemistry ◽  
2013 ◽  
Vol 52 (32) ◽  
pp. 5441-5453 ◽  
Author(s):  
Mengbin Chen ◽  
Naeemah Al-lami ◽  
Marine Janvier ◽  
Edward L. D’Antonio ◽  
Juan A. Faraldos ◽  
...  
Keyword(s):  
Aristolochene Synthase

scholarly journals Protein Epistasis Revealed from Thermostability Profiles of Nicotiana tabacum 5‐epi‐Aristolochene Synthase

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Charisse Crenshaw ◽  
Johnatan Aljadeff ◽  
Irma Fernandez ◽  
Caroline Laurendon ◽  
Marianne Defernez ◽  
...  
Keyword(s):  
Nicotiana Tabacum ◽  
Aristolochene Synthase

The role of aristolochene synthase in diphosphate activation

2012 ◽  
Vol 48 (26) ◽  
pp. 3230 ◽  
Author(s):  
Juan A. Faraldos ◽  
Veronica Gonzalez ◽  
Rudolf K. Allemann
Keyword(s):  
Aristolochene Synthase
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