The article presents algorithms for diagnosing and treatment of patients with H. pylori associated dyspepsia and functional dyspepsia. The importance of testing all patients with dyspepsia for H. pylori infection is emphasized, since H. pylori status has an impact on both therapy and prognosis of disease. Dyspepsia in H. pylori-positive patients is regarded as secondary, associated with H. pylori, and this cohort of patients undergoes anti-Helicopacter therapy. Dyspepsia in H. pylori-negative patients is regarded as functional dyspepsia, if there are relevant diagnostic criteria, and this cohort of patients receives treatment with antisecretory and prokinetic drugs, as well as psychopharmacological medications. Key words: Helicobacter pylori, functional dyspepsia