Systemic contact dermatitis (SCD) is a condition occurring in previously
sensitized individuals after systemic re-exposure to the same or
cross-reacting substance. Pigmented systemic contact dermatitis after
intake of cobalt containing diet has never been reported.
Contact immunotherapy with several sensitizing chemicals such as diphenylcyclopropenone (DPCP) or squaric acid dibutyl ester (SADBE) have been used for the treatment of recalcitrant or multiple warts. Here, we report a case of multiple verrucae vulgaris (VV) on the palm which spontaneously resolved after the development of systemic contact dermatitis against alkyl bromide. We considered that our case accidentally mimics contact immunotherapy against multiple VV. VV sometimes regress spontaneously, which may be triggered by accidental contact dermatitis, as shown in our case.