In order to secure useful information the perceptual system must combine information present in the retinal counterpart of the to-be-discriminated distal variable with information about other variables that affect the state of the retinal counterpart. This combinatorial process may be called—following Woodworth's lead—the process of ‘taking-into-account’. Seven applications of the ‘taking-into-account’ hypothesis are described. Salient features of the hypothesis are examined and the empirical status of the hypothesis is summarized and evaluated. Finally a model of the information-processing sequence suggested by the hypothesis is presented.
Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus.