Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo

Characterization of Kif2a in Xenopus embryos identifies new roles for the Kif2a microtubule depolymerase in coordinating cytokinesis and centrosome coalescence. In addition, defects in mitosis can inhibit large-scale developmental movements in vertebrate tissues.