scholarly journals Relationship between sarcopenia and the serum creatinine/cystatin C ratio in Japanese rural community-dwelling older adults

2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Hiroshi Kusunoki ◽  
Shotaro Tsuji ◽  
Yosuke Wada ◽  
Mayuka Fukai ◽  
Koutatsu Nagai ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Physical Function ◽  
Kidney Function ◽  
Body Fat ◽  
Fat Mass ◽  
Gait Speed ◽  
Community Dwelling ◽  
Muscle Volume ◽  
Body Fat Mass ◽  
Elderly Individuals

Background:Sarcopenia, the age-related decline in skeletal muscle volume and function, is associated with negative clinical and socioeconomic outcomes in elderly people. Clinical biomarkers to diagnose sarcopenia that can be quantified in a reliable, and cost- effective manner, are needed. We investigated whether the creatinine (Cr) /cystatin C (CysC) ratio is correlated with muscle volume and physical function in Japanese community-dwelling elderly subjects. Methods: The present study included 213 men aged 73.2±6.2 years and 464 women aged 72.4±5.5 years from a rural area in the Hyogo prefecture of Japan. To evaluate whether the Cr/CysC ratio is correlated with sarcopenia criteria in elderly individuals with preserved kidney function, we excluded subjects with estimate glomerular filtration rate (eGFR) <45. Results:The prevalence of sarcopenia diagnosed according to the AWGS criteria was 2.8% in men and 3.4% in women. The Cr/CysC ratio correlated with skeletal mass index (r = 0.49, p <0.0001), skeletal muscle mass (r = 0.53, p <0.0001), grip power (r = 0.59, p <0.0001), knee extension muscle strength (r = 0.49, p <0.0001), normal gait speed (r = 0.18, p <0.0001), and maximal gait speed (r = 0.32, p <0.0001). A negative correlation between the Cr/CysC ratio and, body fat mass (r = -0.20, p <0.0001) and percentage of body fat mass (r = -0.39, p <0.0001) was observed. In a multiple regression analysis, Cr/CysC was also found to be significantly positively correlated with each component of the sarcopenia criteria. Conclusions:Even in elderly individuals with preserved kidney function, the Cr/CysC ratio was positively correlated with muscle volume and physical function and negatively correlated with body fat mass. Therefore, the Cr/CysC ratio might be a useful biomarker to predict sarcopenia. 

P1569ADIPONECTIN IS ASSOCIATED WITH DECLINE IS SKELETAL MUSCLE MASS AND BONE MINERAL CONTENT IN PATIENTS ON HEMODIALYSIS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Hiroshi Ogawa ◽  
Toshimitsu Koga ◽  
Daisuke Fuwa ◽  
Hirofumi Tamaki ◽  
Takayuki Nanbu ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Bone Mineral Content ◽  
Muscle Mass ◽  
Body Fat ◽  
Bone Mineral ◽  
Fat Mass ◽  
Skeletal Muscle Mass ◽  
Mineral Content ◽  
Body Fat Mass ◽  
Total Plasma

Abstract Background and Aims Patients on hemodialysis are prone to undernutrition, malnutrition-inflammation-atherosclerosis (MIA) syndrome, and protein-energy wasting (PEW). One of the major adipocytokines adiponectin (ADPN) is involved in anti-arteriosclerotic and anti-inflammatory processes. However, ADPN is implicated in muscle weakness and loss of muscle mass in the elderly in addition to sarcopenia. At the 2019 ERA-EDTA Congress, we announced that total plasma ADPN levels in patients on hemodialysis (HD) showed a significant inverse correlation with BMI, body fat in percentage, mass and estimated skeletal muscle mass, and ADPN may be involved in sarcopenia in patients on HD. Herein, we investigated the association of ADPN level with sarcopenia in patients on HD using a method different from the one used in our previous study. We examined the relationship between total plasma ADPN level and the rate of change in estimated skeletal muscle mass, bone mineral content, and body fat mass over 5 years after the plasma ADPN measurement. Furthermore, we analyzed whether an elevated ADPN level was predictive of a subsequent decline in these parameters. Method Total plasma ADPN levels were measured using ELISA (Bio Vendor-Laboratorni Medicina a.s., Czech Republic) in 42 male patients on HD (age: 51.1 ± 9.0 years, dialysis vintage: 144.8 ± 99.2 months, BMI: 21.8 ± 3.2, dry BW: 62.0 ± 10.9 kg, dialysis time: 15.6 ± 3.1 hours/week). The estimates of skeletal muscle mass, bone mineral content, and body fat mass were made using multi-frequency bioelectrical impedance analysis (MFBIA) within the same year when total plasma ADPN level were first measured in 2011 as well as in 2016. We then calculated the rates of change in the estimated skeletal muscle mass, bone mineral content, and body fat mass over the 5 years and correlated these parameters with the total plasma ADPN measurements. Results Conclusion Total plasma ADPN levels inversely correlate with larger rates of decrease in estimated skeletal muscle mass and bone mineral content in patients on HD. This suggests that ADPN may play a role in the decline in skeletal muscle mass and bone mineral content over time in patients on HD.

scholarly journals Effects of PM2.5 on Skeletal Muscle Mass and Body Fat Mass of the Elderly in Taipei, Taiwan

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Chi-Hsien Chen ◽  
Li-Ying Huang ◽  
Kang-Yun Lee ◽  
Chih-Da Wu ◽  
Hung-Che Chiang ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Skeletal Muscle Mass ◽  
The Elderly ◽  
Body Fat Mass

scholarly journals Effects of Adolescents’ Lifestyle Habits and Body Composition on Bone Mineral Density

2021 ◽  
Vol 18 (11) ◽  
pp. 6170
Author(s):  
ChangSook Han ◽  
HyoKyung Kim ◽  
Suhee Kim
Keyword(s):  
Bone Mineral Density ◽  
Skeletal Muscle ◽  
Bone Mass ◽  
Muscle Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Skeletal Muscle Mass ◽  
Body Fat Mass ◽  
Mineral Density ◽  
Calcium Supplements

The incidence of osteoporosis is increasing as the population ages, as is the need to manage and prevent it. Adolescence is the period when the fastest development of bone mass takes place. Increasing adolescents’ maximum bone mass and avoiding the risk factors for its loss are effective for preventing osteoporosis. This study investigated the factors influencing adolescents’ bone mineral density (BMD). The participants were 126 middle- and high-school students from Gangwon-do; 47.6% (n = 60) were male, with an average age of 15 (range 12–18) years of age. It was found that age, carbonated beverages, snacks, and calcium supplements were variables that showed significant differences in adolescents’ BMD. Additionally, through correlation analysis, it was found that height, weight, body mass index (BMI), body water, protein, minerals, body fat mass, and skeletal muscle mass were correlated with BMD. Multiple regression analysis identified age, calcium supplements, BMI, body fat mass, and skeletal muscle mass as BMD-associated factors. These results show that adolescents’ BMD is higher with lower body fat mass, higher BMI and skeletal muscle mass, and a higher intake of calcium supplements.

scholarly journals Skeletal Muscle Apoptotic Signaling Predicts Thigh Muscle Volume and Gait Speed in Community-Dwelling Older Persons: An Exploratory Study

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e32829 ◽  
Author(s):  
Emanuele Marzetti ◽  
Hazel A. Lees ◽  
Todd M. Manini ◽  
Thomas W. Buford ◽  
Juan M. Aranda ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Gait Speed ◽  
Exploratory Study ◽  
Older Persons ◽  
Community Dwelling ◽  
Muscle Volume ◽  
Thigh Muscle ◽  
Apoptotic Signaling

scholarly journals The Effects of Timing of a Leucine-Enriched Amino Acid Supplement on Body Composition and Physical Function in Stroke Patients: A Randomized Controlled Trial

Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1928 ◽  
Author(s):  
Takashi Ikeda ◽  
Nobuo Morotomi ◽  
Arinori Kamono ◽  
Saki Ishimoto ◽  
Ryo Miyazawa ◽  
...  
Keyword(s):  
Physical Function ◽  
Muscle Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Exercise Intervention ◽  
Controlled Trial ◽  
Exercise Session ◽  
Body Fat Mass ◽  
Stroke Patients ◽  
Post Exercise

The combination of exercise and nutritional intervention is widely used for stroke patients, as well as frail or sarcopenic older persons. As previously shown, supplemental branched chain amino acids (BCAAs) or protein to gain muscle mass has usually been given just after exercise. This study investigated the effect of the timing of supplemental BCAAs with exercise intervention on physical function in stroke patients. The participants were randomly assigned to two groups based on the timing of supplementation: breakfast (n = 23) and post-exercise (n = 23). The supplement in the breakfast group was provided at 08:00 with breakfast, and in the post-exercise group it was provided just after the exercise session in the afternoon at 14:00–18:00. In both groups, the exercise intervention was performed with two sessions a day for two months. The main effects were observed in body fat mass (p = 0.02, confidence interval (CI): 13.2–17.7), leg press strength (p = 0.04, CI: 94.5–124.5), and Berg balance scale (p = 0.03, CI: 41.6–52.6), but no interaction with intake timing was observed. Although the effect of the timing of supplementation on skeletal muscle mass was similar in both groups, BCAA intake with breakfast was effective for improving physical performance and decreasing body fat mass. The results suggest that a combination of BCAA intake with breakfast and an exercise program was effective for promoting rehabilitation of post-stroke patients.

scholarly journals Association between the recognition of muscle mass and exercise habits or eating behaviors in female college students

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Tomoki Mase ◽  
Kumiko Ohara ◽  
Katsumasa Momoi ◽  
Harunobu Nakamura
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Body Shape ◽  
Eating Behaviors ◽  
Shape Perception ◽  
Body Fat Mass ◽  
Exercise Habits ◽  
Post Hoc

AbstractThis study aimed to examine the association between muscle mass and perception of body shape, desired body shape, physical strength, exercise habits, and eating behaviors. Height, weight, and body composition in 270 female university students were measured. The questionnaire on body shape perception, desired body shape, dieting experience, current, and past exercise habits, exercise preference, and eating behaviors were administered. The analysis of covariance with body fat mass as the covariate found that the skeletal muscle index (SMI) was different among each group on each of body perception or desired body shape (all, p < 0.001). In the post hoc test on body shape perception, the SMI in “obese” was significantly more than that in “slim” (p < 0.001) and “normal” (p < 0.001). In the desired body shape, the SMI in “become thin” was more than that in “maintain as current shape” (p < 0.001). Further, a significant difference was found among the categories of diet experience, with body fat mass as the covariate. In the post hoc test, the SMI in “yes” was more than that in “no” (p < 0.001). These results indicate that not only body fat mass but skeletal muscle mass drives young females’ desire for thinness even with exercise advantages.

Increased body fat mass and tissue lipotoxicity associated with ovariectomy or high-fat diet differentially affects bone and skeletal muscle metabolism in rats

2014 ◽  
Vol 54 (7) ◽  
pp. 1139-1149 ◽  
Author(s):  
Camille Tagliaferri ◽  
Jérôme Salles ◽  
Jean-François Landrier ◽  
Christophe Giraudet ◽  
Véronique Patrac ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Body Fat ◽  
Fat Mass ◽  
High Fat Diet ◽  
Muscle Metabolism ◽  
Body Fat Mass ◽  
High Fat ◽  
Skeletal Muscle Metabolism

scholarly journals EFFECTS OF A 6-WEEK CONTROLED EXERCISE PROGRAM AND SEMI-CONTROLED DIET ON BODY FAT AND SKELETAL MUSCLE MASS IN ADULTS

2019 ◽  
Vol 19 (1) ◽  
pp. 7-14 ◽  
Author(s):  
F Kukić ◽  
N Todorović ◽  
N Cvijanović
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Skeletal Muscle Mass ◽  
Body Height ◽  
Exercise Program ◽  
Body Fat Mass ◽  
Dietary Regimen

Aim. To investigate the effects of a 6-week of controlled exercise program followed by a semi-controlled dietary regimen on indicators of body fat mass (BF) and skeletal muscle mass (SMM) of adults. Materials and methods. The sample consisted of 28 particpants with the main characteristics of the sample being: age = 29.70 ± 8.35 years, body height (BH) = 177.35 ± 9.36 cm, and body mass (BM) = 105.20 ± 27.06 kg. Body composition parameters, BM, body fat mass (BF), trunk fat (TF), skeletal muscle mass (SMM), percent of body fat (PBF), percent of skeletal muscle mass (PSMM), body mass index (BMI), and index of hypokinesia (IH) were collected before and after six weeks of exercise program and semi-controlled diet regimen. A Paired sample T-test and effect size (ES) were used to determine the effects and their magnitude of the treatment applied. Results. A 6-week treatment significantly affected investigated variables, wherein BF (–6.75 kg, p < 0.001), TF (–3.28 kg, p < 0.001), and SMM (–0.91 kg, p = 0.003) tissue decreased in a different degree, leading to a small but highly significant increase in PSMM (2.60 %, p < 0.001). A decrease in BF and SMM resulted in a significant reduction in BMI, while IH decreased in a smaller degree than BMI because PBF and PSMM changed inversely. Conclusion. Six weeks of a controlled exercise program 3 times/week and semi-controlled diet is an effective approach to the reduction of BM, BF, and TF and to increasing the movement potential by changing the proportions of PBF and PSMM.

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