Elevated Serum Digoxin Level Associated With Coadministered Fluoxetine

1998 ◽  
Vol 158 (10) ◽  
pp. 1152 ◽  
Author(s):  
Arthur Leibovitz ◽  
Tamara Bilchinsky ◽  
Israel Gil ◽  
Beni Habot
1986 ◽  
Vol 12 (3) ◽  
pp. 261-266
Author(s):  
HIROSHI HISHIDA ◽  
SEIICHI KOYAMA ◽  
AKIRA TAKAHASHI ◽  
YASUHARU ABE ◽  
TATUO SUZUKI ◽  
...  

1983 ◽  
Vol 17 (4) ◽  
pp. 286-288 ◽  
Author(s):  
Frank P. Quattrocchi ◽  
J. Daniel Robinson ◽  
R. Whit Curry ◽  
Mario L. Grieco ◽  
Stephen G. Schulman

This study was undertaken to determine the effects of ibuprofen (Motrin), in daily doses of at least 1600 mg, on steady-state digoxin concentrations. A total of 12 ambulatory patients (10, female; 2, male), with a mean age of 66 years (38–81 yr), completed the study. An initial baseline serum digoxin level was obtained, with follow-up levels at 7 days and, whenever possible, 28 days after ibuprofen initiation. Serum creatinine concentrations were not significantly different from baseline to 7 or 28 days of ibuprofen therapy. Results show a statistically significant (p < 0.05) increase in digoxin levels after seven days of ibuprofen. The mean increase was 59 percent (range, 10.7–325.4 percent), with 10 of the 12 patients displaying increased seven-day levels. Digoxin levels drawn 28 days after ibuprofen initiation were not statistically different from baseline or seven-day digoxin levels.


1991 ◽  
Vol 17 (4) ◽  
pp. 218-228
Author(s):  
TSUTOMU KURODA ◽  
YASUAKI HASHIMOTO ◽  
KUMIKO TASHIRO ◽  
YASUHIRO YOSHIHARA ◽  
TETSUYA INATOME ◽  
...  

1981 ◽  
Vol 11 (1) ◽  
pp. 69
Author(s):  
Seong Yun Kim ◽  
Jung Kun Lim ◽  
Ye Hwe Kim ◽  
Young Woo Lee ◽  
Sung Ho Lee

Author(s):  
Takatsugu YAMAMOTO ◽  
Kikuo TAKANO ◽  
Masaki SANAKA ◽  
Yuichi KOIKE ◽  
Satoru MINESHITA

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