Oral Acyclovir Reduces the Incidence of Recurrent Herpes Simplex Keratitis in Rabbits After Penetrating Keratoplasty

1989 ◽  
Vol 107 (8) ◽  
pp. 1200 ◽  
Author(s):  
Craig F. Beyer
Keyword(s):  
Herpes Simplex ◽  
Penetrating Keratoplasty ◽  
Oral Acyclovir ◽  
Recurrent Herpes ◽  
Herpes Simplex Keratitis

Effect of Prophylactic Oral Acyclovir After Penetrating Keratoplasty for Herpes Simplex Keratitis

Cornea ◽  
2007 ◽  
Vol 26 (8) ◽  
pp. 930-934 ◽  
Author(s):  
Denise D Garcia ◽  
Qais Farjo ◽  
David C Musch ◽  
Alan Sugar
Keyword(s):  
Herpes Simplex ◽  
Penetrating Keratoplasty ◽  
Oral Acyclovir ◽  
Herpes Simplex Keratitis

Recurrent Herpes Simplex Keratitis After Penetrating Keratoplasty

2009 ◽  
Vol 50 (5) ◽  
pp. 657 ◽  
Author(s):  
In Young Jeong ◽  
Kwang Hoon Lee ◽  
In Cheon You ◽  
Kyung Chul Yoon
Keyword(s):  
Herpes Simplex ◽  
Penetrating Keratoplasty ◽  
Recurrent Herpes ◽  
Herpes Simplex Keratitis

scholarly journals Immunological Aspects of Acute and Recurrent Herpes Simplex Keratitis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Jacek Rolinski ◽  
Iwona Hus
Keyword(s):  
Herpes Simplex ◽  
Current Knowledge ◽  
Ocular Infection ◽  
Corneal Scarring ◽  
Recurrent Herpes ◽  
Chronic Inflammatory Reaction ◽  
Herpes Simplex Keratitis ◽  
Methods Of Treatment ◽  
Therapeutical Options

Herpes simplex keratitis (HSK) belongs to the major causes of visual morbidity worldwide and available methods of treatment remain unsatisfactory. Primary infection occurs usually early in life and is often asymptomatic. Chronic visual impairment and visual loss are caused by corneal scaring, thinning, and vascularization connected with recurrent HSV infections. The pathogenesis of herpetic keratitis is complex and is still not fully understood. According to the current knowledge, corneal scarring and vascularization are the result of chronic inflammatory reaction against HSV antigens. In this review we discuss the role of innate and adaptive immunities in acute and recurrent HSV ocular infection and present the potential future targets for novel therapeutical options based on immune interventions.

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