scholarly journals Oral antivirals for preventing recurrent herpes simplex keratitis in people with corneal grafts

Author(s):  
Uday K Bhatt ◽  
MN Abdul Karim ◽  
Jeremy I Prydal ◽  
Senthil V Maharajan ◽  
Usama Fares
2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Jacek Rolinski ◽  
Iwona Hus

Herpes simplex keratitis (HSK) belongs to the major causes of visual morbidity worldwide and available methods of treatment remain unsatisfactory. Primary infection occurs usually early in life and is often asymptomatic. Chronic visual impairment and visual loss are caused by corneal scaring, thinning, and vascularization connected with recurrent HSV infections. The pathogenesis of herpetic keratitis is complex and is still not fully understood. According to the current knowledge, corneal scarring and vascularization are the result of chronic inflammatory reaction against HSV antigens. In this review we discuss the role of innate and adaptive immunities in acute and recurrent HSV ocular infection and present the potential future targets for novel therapeutical options based on immune interventions.


2015 ◽  
Vol 128 (1) ◽  
pp. 46-50 ◽  
Author(s):  
Xin Wang ◽  
Linnong Wang ◽  
Nianlang Wu ◽  
Xinjun Ma ◽  
Jianjiang Xu

2013 ◽  
Vol 131 (10) ◽  
pp. 1372 ◽  
Author(s):  
Nathaniel Nataneli ◽  
Jean S. M. Chai ◽  
Eric D. Donnenfeld ◽  
Henry D. Perry

2013 ◽  
Vol 97 (9) ◽  
pp. 1113-1117 ◽  
Author(s):  
Godefroy Kaswin ◽  
Antoine Rousseau ◽  
Mohamed M'Garrech ◽  
Emmanuel Barreau ◽  
Nicolas Pogorzalek ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document