BENIGN FOREIGN BODY GIANT-CELL TUMORS IN THE LONG BONES

JAMA ◽  
1924 ◽  
Vol 83 (17) ◽  
pp. 1323 ◽  
Author(s):  
HENRY W. MEYERDING
2019 ◽  
Vol 72 (8) ◽  
pp. 550-553 ◽  
Author(s):  
Martin J Magers ◽  
Hristos Z Kaimakliotis ◽  
Marcelo P Barboza ◽  
Elhaam Bandali ◽  
Nabil Adra ◽  
...  

AimsTo describe a large tertiary care academic centre’s experience with patients who achieve a complete pathological response (ie, ypT0N0) following neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) with emphasis on morphological features present in the RC and clinical outcome.Methods41 patients with ypT0N0 disease following transurethral resection of bladder tumour (TURBT), NAC and RC with available clinical follow-up information were analysed. Slides from all RCs were reviewed to confirm pathological stage and assess for morphological parameters (eg, foreign body giant cell reaction, dystrophic calcification, scar and fat necrosis).ResultsWith median follow-up of 32.8 months, the recurrence-free survival at 1 and 5 years was 97.4% and 93.5%, while the overall survival at 3 and 5 years was 94.2% and 88.6%, respectively. No patients died of urothelial carcinoma. Stage assigned at TURBT was 1 pTa (2%), 1 pT1 (2%), 38 pT2 (93%) and 1 pT3a (2%). 17 TURBTs demonstrated variant histology, with the majority of these being squamous (65%). The most common morphological features present at RC were scar (100%), foreign body giant cell reaction (80%), chronic inflammation within lamina propria (68%) and dystrophic calcifications (39%). Other morphological features were less common or absent.ConclusionypT0N0 disease at RC portends an excellent prognosis, regardless of stage or variant histology in the TURBT; scar, foreign body giant cell reaction, chronic inflammation and dystrophic calcifications are often present.


1995 ◽  
Vol 19 (4) ◽  
pp. 628-630 ◽  
Author(s):  
Catherine C. Moran ◽  
Saeed T. Vakili ◽  
Karen S. Caldemeyer ◽  
Richard R. Smith

2008 ◽  
Vol 86A (2) ◽  
pp. 535-543 ◽  
Author(s):  
Amy K. McNally ◽  
Jacqueline A. Jones ◽  
Sarah R. MacEwan ◽  
Erica Colton ◽  
James M. Anderson

2009 ◽  
Vol 91 (4) ◽  
pp. 945-949 ◽  
Author(s):  
Umile Giuseppe Longo ◽  
Francesco Franceschi ◽  
Laura Ruzzini ◽  
Carla Rabitti ◽  
Nicola Maffulli ◽  
...  

2007 ◽  
Vol 171 (2) ◽  
pp. 632-640 ◽  
Author(s):  
Steven M. Jay ◽  
Eleni Skokos ◽  
Farah Laiwalla ◽  
Marie-Marthe Krady ◽  
Themis R. Kyriakides

2017 ◽  
Vol 105 (9) ◽  
pp. 2441-2450 ◽  
Author(s):  
Sujan Lamichhane ◽  
Jordan A. Anderson ◽  
Thomas Vierhout ◽  
Tyler Remund ◽  
Hongli Sun ◽  
...  

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