Lithium Treatment of Manic-Depressive Illness

JAMA ◽  
1988 ◽  
Vol 259 (12) ◽  
pp. 1834 ◽  
Author(s):  
Mogens Schou
Keyword(s):  
Lithium Treatment ◽  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Manic Depressive

Practical Aspects of Long-Term Treatment with Lithium

1992 ◽  
Vol 6 (2_suppl) ◽  
pp. 330-333 ◽  
Author(s):  
Iain Glen
Keyword(s):  
Lithium Treatment ◽  
Depressive Illness ◽  
Term Treatment ◽  
Term Therapy ◽  
Manic Depressive Illness ◽  
Short Term Treatment ◽  
Manic Depressive ◽  
Long Term Treatment ◽  
Long Term Therapy

There is no increase in the overall mortality of patients undergoing long-term lithium treatment compared with those receiving short-term treatment. Lithium causes a reduction in the incidence of suicide in patients suffering from manic depressive illness. Long-term treatment with lithium is more effective than treatment with imipramine or amitriptyline. Drug interactions may cause problems during long-term therapy with lithium. A reduction in plasma levels of lithium should be considered in stable patients on long-term prophylaxis. Discontinuation of therapy often results in a relapse. The toxicity of lithium is related to its effects on calcium transport.

Pretreatment Episode Count and Response to Lithium Treatment in Manic-Depressive Illness

2003 ◽  
Vol 11 (5) ◽  
pp. 245-256 ◽  
Author(s):  
Irene Bratti ◽  
Ross Baldessarini ◽  
Christopher Baethge ◽  
Leonardo Tondo
Keyword(s):  
Lithium Treatment ◽  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Manic Depressive

Artistic Productivity and Lithium Prophylaxis in Manic-Depressive Illness

1979 ◽  
Vol 135 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Mogens Schou
Keyword(s):  
Lithium Treatment ◽  
Significant Degree ◽  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Individual Sensitivity ◽  
Creative Power ◽  
Manic Depressive

SummaryTwenty-four manic-depressive artists, in whom prophylactic lithium treatment had attenuated or prevented recurrences to a significant degree, were questioned about their creative power during the treatment. Twelve artists reported increased artistic productivity, six unaltered productivity, and six lowered productivity. The effect of lithium treatment on artistic productivity may depend on the severity and type of the illness, on individual sensitivity, and on habits of utilizing manic episodes productively.

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