Stereospecific Reduction of Methyl o-Chlorobenzoylformate at 300 g⋅L−1 without Additional Cofactor using a Carbonyl Reductase Mined from Candida glabrata

2012 ◽  
Vol 354 (9) ◽  
pp. 1765-1772 ◽  
Author(s):  
Hongmin Ma ◽  
Linlin Yang ◽  
Yan Ni ◽  
Jie Zhang ◽  
Chun-Xiu Li ◽  
...  
2020 ◽  
Vol 10 (17) ◽  
pp. 5925-5934 ◽  
Author(s):  
Sneha Sudhakara ◽  
Chandrasekaran Ramakrishnan ◽  
M. Michael Gromiha ◽  
Anju Chadha

The quantum mechanics/molecular mechanics study of an (S) specific carbonyl reductase from C. parapsilosis ATCC 7330 showing a dual kinetic response for the reduction of ketones and α-ketoesters suggests different reaction mechanisms for the same.


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