Closed‐Loop Temperature‐Controlled Magnetic Hyperthermia Therapy with Magnetic Guidance of Superparamagnetic Iron‐Oxide Nanoparticles

2022 ◽  
pp. 2100237
Author(s):  
Awais Ahmed ◽  
Eunhee Kim ◽  
Sungwoong Jeon ◽  
Jin‐Young Kim ◽  
Hongsoo Choi
2018 ◽  
Vol 2 (1) ◽  

Superparamagnetic iron oxide nanoparticles (SPIONs) have found extensive applications in both cancer therapy and diagnosis (theranostics) due to their intrinsic magnetic properties. SPIONs can be applied as contrast agents in magnetic resonance imaging while they are considered as efficacious drug carriers for targeted therapeutic systems as well as hyperthermia therapy. In this article, recent advances in application of SPIONs in the realm of cancer theranostics are reviewed. Moreover, biosafety issues arising from SPION application are briefly mentioned.


2014 ◽  
Vol 802 ◽  
pp. 535-539 ◽  
Author(s):  
Fernanda A. Sampaio da Silva ◽  
Edwin E.G. Rojas ◽  
Sérgio Romero ◽  
Marcos Flávio de Campos

Nowadays, superparamagnetic iron oxide nanoparticles are an important tool for cancer treatment, such as magnetic hyperthermia. The goal is heating diseased tissue and then tumor cells are destroyed. Magnetic nanoparticles are promising mainly because they have specific ability to reduce side effects. However, forin vivoapplications, nanoparticles need to be coated by a biocompatible material. In this work, nanoparticles are coated by PEG (biocompatible polymer). Samples were produced by coprecipitation process. Information about particle size, magnetic properties and crystallinity were obtained.


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