Oxide Nanoparticles
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2021 ◽  
Vol 226 ◽  
pp. 112844
Ali Raza Khan ◽  
Wardah Azhar ◽  
Junyu Wu ◽  
Zaid Ulhassan ◽  
Abdul Salam ◽  

2021 ◽  
Vol 29 (5) ◽  
pp. 34-42
Boris Aleksandrovich Katsnelson ◽  
Ivan Nikolaevich Chernyshov ◽  
Svetlana Nikolaevna Solovyeva ◽  
Ilzira Amirovna Minigalieva ◽  
Vladimir Borisovich Gurvich ◽  

Introduction. Nickel oxide nanoparticles are of interest for toxicological science, not only as engineered nanoparticles, producing for industrial and scientific needs, but also as spontaneous pollutants of the atmosphere and the working area in industrial processes related to metallurgy and welding. Materials and methods. Rats were exposed to nickel-oxide aerosol at a concentration of 2.4 ± 0.4 µg/m3 in a “nose only” inhalation setup for 4 hours at a time, 5 times a week, during an overall period of 2 weeks to 6 months. Results. Of the several dozen examined parameters, only a few statistically significant manifestations associated with the reaction of the deep airways to inhaled nanoparticles were noted. However, in the biochemical and morphometric parameters of the lungs, even at the longest periods of exposure, the intergroup differences were insignificant. At the same time, even from the first weeks of the exposure period, genotoxic and allergic indices shifts are detected. Conclusion. For most of the evaluated effects, this level of exposure to nickel oxide nanoparticles may be considered as close to LOAEL, or even to NOAEL. However, according to some indicators, there are effects that suggest a non-threshold nature.

2021 ◽  
Vol 282 ◽  
pp. 116923
Priyanka Rani ◽  
M. Basheer Ahamed ◽  
Kalim Deshmukh

2021 ◽  
Vol 7 (10) ◽  
pp. 25-30
A. Mametova ◽  
R. Zharkynbaeva ◽  
K. Gafforova ◽  
Zh. Abdullaeva

Research relevance is the study of iron-containing nanocomposites based on humic substances is their special properties, composition, structure and applications. Materials and research methods: the article was compiled using a literature review of publications on iron-containing nanocomposites based on humic substances. Research objectives: determination of the structure and types of iron-containing nanocomposites based on humic substances and their field of application in medicine. Research results: Iron oxide nanoparticles are applicable in the development of nanomedicine due to their adaptable functions. Humic substances are composed of supramolecular heteropolymers, which include natural objects. Conclusions: Iron-containing nanocomposites can be used in biomedicine as diagnostic and therapeutic tools. Humic substances are organic macromolecules with multiple properties and high structural complexity.

2021 ◽  
Vol 31 (4) ◽  
pp. 38-45

Iron oxide nanoparticles have been known to be non-toxic and are among the most widely used nanomaterials in life, from the medical, agricultural to environmental fields. However, so far, the understanding of the interaction of nanoparticles, in general, and iron oxide nanoparticles, in particular, with the environment and the flora and fauna ecosystems is still limited. This study evaluated the effects of ferrite (Fe3O4) nanoparticles in soil on the growth of peas (Pisum sativum) and bok choy (Brassica rapa). The study showed that the nanoparticle concentration of 25 mg/kg of soil had the best positive effect on peas growth in terms of the main root elongation and root water retention. At a concentration of 25 mg/kg of soil, iron oxide nanoparticles did not affect the dry biomass growth of root and plant in peas and bok choy, respectively, even in the presence of potassium sulfate in soil. This suggests that the effect of ferric oxide nanoparticles could be more dominant than that of potassium sulfate fertilizer while maintaining constant biomass with increasing water uptake. Further studies at the cellular and tissue levels are needed to better understand this issue.

Water ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 2876
Mian Fawaz Ahmed ◽  
Muhammad Asad Abbas ◽  
Azhar Mahmood ◽  
Nasir M. Ahmad ◽  
Hifza Rasheed ◽  

Water contaminated with highly hazardous metals including arsenic (As) is one of the major challenges faced by mankind in the present day. To address this pressing issue, hybrid beads were synthesized with various concentrations of zero valent iron oxide nanoparticles, i.e., 20% (FeCh-20), 40% (FeCh-40) and 60% (FeCh-60) impregnated into a polymer of chitosan. These hybrid beads were employed as an adsorbent under the optimized conditions of pH and time to facilitate the efficient removal of hazardous arsenic by adsorption cum reduction processes. X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), Brunauer- Emmett-Teller BET, a porosity test and wettability analysis were performed to characterize these hybrid beads. The porosity and contact angle of the prepared hybrid beads decreased with an increase in nanoparticle concentration. The effects of various adsorption factors such as adsorbent composition, contact period, pH value and the initial adsorbate concentration were also evaluated to study the performance of these beads for arsenic treatment in contaminated water. FeCh-20, FeCh-40 and FeCh-60 have demonstrated 63%, 81% and 70% removal of arsenic at optimized conditions of pH 7.4 in 10 h, respectively. Higher adsorption of arsenic by FeCh-40 is attributed to its optimal porosity, hydrophilicity and the presence of appropriate nanoparticle contents. The Langmuir adsorption kinetics described the pseudo second order. Thus, the novel beads of FeCh-40 developed in this work are a potent candidate for the treatment of polluted water contaminated with highly toxic arsenic metals.

Biomedicines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1462
Nadine Wiesmann ◽  
Simone Mendler ◽  
Christoph R. Buhr ◽  
Ulrike Ritz ◽  
Peer W. Kämmerer ◽  

Due to the demographic change, medicine faces a growing demand for tissue engineering solutions and implants. Often, satisfying tissue regeneration is difficult to achieve especially when co-morbidities hamper the healing process. As a novel strategy, we propose the incorporation of zinc oxide nanoparticles (ZnO NPs) into biomaterials to improve tissue regeneration. Due to their wide range of biocompatibility and their antibacterial properties, ZnO NPs are already discussed for different medical applications. As there are versatile possibilities of modifying their form, size, and function, they are becoming increasingly attractive for tissue engineering. In our study, in addition to antibacterial effects of ZnO NPs, we show for the first time that ZnO NPs can foster the metabolic activity of fibroblasts as well as endothelial cells, both cell types being crucial for successful implant integration. With the gelatin sponge method performed on the chicken embryo’s chorioallantoic membrane (CAM), we furthermore confirmed the high biocompatibility of ZnO NPs. In summary, we found ZnO NPs to have very favorable properties for the modification of biomaterials. Here, incorporation of ZnO NPs could help to guide the tissue reaction and promote complication-free healing.

Chandana Malakar ◽  
Kaustuvmani Patowary ◽  
Suresh Deka ◽  
Mohan Chandra Kalita

Molecules ◽  
2021 ◽  
Vol 26 (20) ◽  
pp. 6163
Aree Choodum ◽  
Nareumon Lamthornkit ◽  
Chanita Boonkanon ◽  
Tarawee Taweekarn ◽  
Kharittha Phatthanawiwat ◽  

Benzo(a)pyrene (BaP) has been recognized as a marker for the detection of carcinogenic polycyclic aromatic hydrocarbons. In this work, a novel monolithic solid-phase extraction (SPE) sorbent based on graphene oxide nanoparticles (GO) in starch-based cryogel composite (GO-Cry) was successfully prepared for BaP analysis. Rice flour and tapioca starch (gel precursors) were gelatinized in limewater (cross-linker) under alkaline conditions before addition of GO (filler) that can increase the ability to extract BaP up to 2.6-fold. BaP analysis had a linear range of 10 to 1000 µgL−1 with good linearity (R2 = 0.9971) and high sensitivity (4.1 ± 0.1 a.u./(µgL−1)). The limit of detection and limit of quantification were 4.21 ± 0.06 and 14.04 ± 0.19 µgL−1, respectively, with excellent precision (0.17 to 2.45%RSD). The accuracy in terms of recovery from spiked samples was in the range of 84 to 110% with no significant difference to a C18 cartridge. GO-Cry can be reproducibly prepared with 2.8%RSD from 4 lots and can be reused at least 10 times, which not only helps reduce the analysis costs (~0.41USD per analysis), but also reduces the resultant waste to the environment.

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Nattanan Panjaworayan T-Thienprasert ◽  
Jiraroj T-Thienprasert ◽  
Jittiporn Ruangtong ◽  
Thitiradsadakorn Jaithon ◽  
Pattana Srifah Huehne ◽  

Fungicides have been extensively used to control fungal diseases that affect several crops including ornamental crops. However, concerns have arisen due to a development of fungicide resistance and increasing incidences of fungicide toxicity effects on nontarget organisms. As zinc oxide nanoparticles (ZnO NPs) have demonstrated effective antimicrobial activity, this study is therefore aimed at synthesizing ZnO NPs from banana peels using a green chemistry method in a large scale and determines their physical properties including their inhibitory effects against a plant pathogen fungus causing anthracnose in orchids, Colletotrichum sp. Results from X-ray diffraction and scanning electron microscope indicated that the synthesized ZnO NPs were obtained without other crystalline impurities, and they were spherical in shape with the average diameter of 256 ± 40   nm , respectively. The absorption peak was found to be centered at ~370 nm with the optical band gap value approximately 2.8 eV. Fourier transform infrared spectroscopy analysis confirmed the presence of several functional groups on synthesized ZnO NPs. The total amount of synthesized ZnO NPs was obtained about 170 g for a synthesis reaction. By performing the antifungal activity assay, high doses of green synthesized ZnO NPs significantly inhibited growth of isolated Colletotrichum sp. (KUFC 021) on culture plates. Under greenhouse conditions, high doses of synthesized ZnO NPs also significantly reduced anthracnose symptoms on inoculated orchid leaves with the Colletotrichum sp. (KUFC 021).

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